2-(p-Nitrophenyl)acetoacetic acid ethyl ester

Base Information

Chemical Name:2-(p-Nitrophenyl)acetoacetic acid ethyl ester
CAS No.:10565-18-1
Molecular Formula:C12H13NO5
Molecular Weight:251.239
Hs Code.:2918300090
Mol file:10565-18-1.mol

Synonyms:2-(p-Nitrophenyl)acetoacetic acid ethyl ester;α-Acetyl-4-nitrobenzeneacetic acid ethyl ester

Suppliers and Price of 2-(p-Nitrophenyl)acetoacetic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(p-Nitrophenyl)acetoacetic acid ethyl ester

Chemical Property:

PSA：89.19000
LogP:2.35370

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(p-Nitrophenyl)acetoacetic acid ethyl ester

There total 6 articles about 2-(p-Nitrophenyl)acetoacetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 141-97-9
ethyl acetoacetate

: (4-nitrophenyl)(phenyl)iodonium tetrafluoroborate

: 10565-18-1
Ethyl 2-(4-nitrophenyl)-3-oxobutanoate

Guidance literature:: ethyl acetoacetate; With potassium tert-butylate; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h; Inert atmosphere;

(4-nitrophenyl)(phenyl)iodonium tetrafluoroborate; In N,N-dimethyl-formamide; at 0 - 20 ℃; chemoselective reaction; Inert atmosphere;
DOI:10.1021/jo5023958

Reference yield: 43.0%

: 141-97-9
ethyl acetoacetate

: 100-00-5
4-chlorobenzonitrile

: 10565-18-1
Ethyl 2-(4-nitrophenyl)-3-oxobutanoate

Guidance literature:: With potassium phosphate; palladium diacetate; XPhos; In toluene; at 90 ℃; for 16h; Inert atmosphere;

Reference yield: 30.0%

: 636-98-6
p-nitrobenzene iodide

: 141-97-9
ethyl acetoacetate

: 1528-74-1
4,4'-dinitrobiphenyl

: 10565-18-1
Ethyl 2-(4-nitrophenyl)-3-oxobutanoate

: 98-95-3,26969-40-4
nitrobenzene

Guidance literature:: With copper(l) iodide; sodium hydride; Yield given. Multistep reaction; 1.) DMF, 2.) 140 deg C, 4 h;;
DOI:10.1246/bcsj.58.1597