53600-33-2

Basic information

• Product Name: 2-Amino-6-methoxybenzoic acid
• Synonyms: 6-METHOXYANTHRANILIC ACID;6-METHOXYANTHRANILLIC ACID;2-AMINO-6-METHOXYBENZOIC ACID;BUTTPARK 89\07-38;2-AMINO-6-METHOXYBENZOIC ACID 98%;2-Amion-6-methoxybenzoic acid ,98%;2-Carboxy-3-methoxyaniline, 3-Amino-2-carboxyanisole, 6-Methoxyanthranilic acid, 6-Amino-o-anisic acid;2-Amion-6-methoxybenzoic acid
• CAS NO: 53600-33-2
• Molecular Formula: C₈H₉NO₃
• Molecular Weight: 167.16
• Product Categories: Amino Acids and Derivatives;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Carboxylic Acids;Phenyls & Phenyl-Het;Phenylacetic acid;Carboxylic Acids;Phenyls & Phenyl-Het
• Mol File: 53600-33-2.mol
• Article Data: 6

Chemical Properties

• Melting Point: >85(dec.)
• Boiling Point: 341.5 °C at 760mmHg
• Flash Point: 160.4 °C
• Appearance: /
• Density: 1.303 g/cm³
• Vapor Pressure: 3.08E-05mmHg at 25°C
• Refractive Index: 1.603
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 4.83±0.10(Predicted)
• CAS DataBase Reference: 2-Amino-6-methoxybenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-6-methoxybenzoic acid(53600-33-2)
• EPA Substance Registry System: 2-Amino-6-methoxybenzoic acid(53600-33-2)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 53600-33-2(Hazardous Substances Data)

Usage

Chemical Properties

Off-white to light yellow solid

Uses

2-Amino-6-methoxybenzoic acid is a reagent is the synthesis of Tasquinimod (T007820). Tasquinimod is an orally active antiangiogenic agent which may inhibit HDAC4 signalling. This affects cancer cell survival thus making this compound and anti-cancer agent.

InChI:InChI=1/C8H9NO3/c1-12-6-4-2-3-5(9)7(6)8(10)11/h2-4H,9H2,1H3,(H,10,11)

Upstream product

• 53967-73-0 2-nitro-6-methoxybenzoic acid 
• 1591-37-3 2-amino-6-methoxybenzonitrile 
• 37439-78-4 N-(3-(allyloxy)phenyl)acetamide 
• 38469-85-1 2-methoxy-6-nitrobenzonitrile 
• 4837-88-1 6-methoxy-2-nitrotoluene 
• 5460-31-1 3-nitro-o-cresol 
• 64208-72-6 2-chloromethyl-3-nitro-anisole 
• 855157-00-5 2-chloromethyl-3-nitro-phenol 
• 37439-79-5 2-allyl-3-acetamidophenol 
• 340774-74-5 acetic acid-(2-allyl-3-methoxy-anilide) 
• 536-90-3 m-Anisidine 
• 60144-52-7 tert-butyl 3-methoxyphenylcarbamate 
• 77901-52-1 methyl 2-methoxy-6-nitrobenzoate 
• 42087-82-1 methyl 2,6-dinitrobenzoate 

Downstream Products

• 54166-66-4 2'-carboxy-3'-methoxyoxanilic acid ethyl ester 
• 67765-42-8 5-methoxy-2,4-dihydro-1H-3,1-benzoxazine-2,4-dione 
• 112239-07-3 2-Methoxy-6-(2-methoxycarbonyl-phenylamino)-benzoic acid 
• 102421-40-9 6,7,8-Trimethoxy-3,4-dihydro-2a-aza-benzo[fg]aceanthrylene-1,2-dione 
• 102421-41-0 2,3,9-Trimethoxy-13-(3-methoxy-phenyl)-5,6-dihydro-isoquino[3,2-a]isoquinolin-8-one 
• 567-62-4 2-amino-5-hydroxybenzoic acid 
• 19532-68-4 2,2'-dithiobis(6-methoxybenzoic acid) 
• 1026506-57-9 C₁₆H₁₄O₆Se₂ 
• 66195-39-9 N-benzyl-2-iodo-6-methoxybenzamide 
• 103204-98-4 S-<2-Carboxy-3-methoxy-phenyl>-thioglykolsaeure 
• 1027553-82-7 2-(4-bromo-3-phenoxy-phenyl)-5-methoxy-benzo[d][1,3]oxazin-4-one 
• 944060-97-3 C₈H₈O₃S 
• 681247-48-3 methyl 6-amino-3-bromo-2-methoxybenzoate 

Relevant articles and documents

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The present invention relates to pyridazino[4,5-b]quinolines, and pharmaceutically useful salts thereof, which are excitatory amino acid antagonists and which are useful when such antagonism is desired such as in the treatment of neurological disorders. The invention further provides pharmaceutical compositions containing pyridazino[4,5-b]quinolines as active ingredient, and methods for the treatment of neurological disorders.

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Substituted benzoxazin-2-ones and pharmaceutical compositions containing them

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