1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol

Base Information

Chemical Name:1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol
CAS No.:923170-94-9
Molecular Formula:C10H9F3O3
Molecular Weight:234.1718696
Hs Code.:2932999099
DSSTox Substance ID:DTXSID70585379
Mol file:923170-94-9.mol

Synonyms:923170-94-9;1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol;1-(2,3-dihydro-1,4-benzodioxin-6-yl)-2,2,2-trifluoroethanol;1-(2,3-dihydro-1,4-benzodioxin-6-yl)-2,2,2-trifluoroethan-1-ol;1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethan-1-ol;SCHEMBL12181345;DTXSID70585379;QBFYQMMKZRQMBH-UHFFFAOYSA-N;alpha-(Trifluoromethyl)-2,3-dihydrobenzo[b][1,4]dioxine-6-methanol;MFCD08444244;AKOS009092630;SY249785;CS-0270646;EN300-24371;J-502897;Z188898088

Suppliers and Price of 1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol 95+%
1g
$ 432.00

Chemenu
1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethan-1-ol 95%
1g
$ 408.00

Alichem
1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol
1g
$ 387.20

AK Scientific
1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol
5g
$ 1126.00

Total 9 raw suppliers

Chemical Property of 1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol

Chemical Property:

PSA：38.69000
LogP:2.05350
Storage Temp.:2-8°C
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:234.05037863
Heavy Atom Count:16
Complexity:244

Purity/Quality:

97% ^*data from raw suppliers

1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC2=C(O1)C=CC(=C2)C(C(F)(F)F)O

Technology Process of 1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol

There total 3 articles about 1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 81290-20-2
(trifluoromethyl)trimethylsilane

: 923170-94-9
1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol

Guidance literature:: 2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde; (trifluoromethyl)trimethylsilane; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 4h;

With water; In N,N-dimethyl-formamide; for 4h; Acidic conditions;
DOI:10.1016/j.tetlet.2013.06.045

Reference yield: 89.0%

: 923170-94-9
1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 1h;

Reference yield: 84.0%

: 1400691-55-5
C₉H₁₆N₂*C₃H₂F₆O₂

: 29668-44-8
2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde

: 923170-94-9
1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,2,2-trifluoroethanol

Guidance literature:: C₉H₁₆N₂*C₃H₂F₆O₂; With potassium tert-butylate; tetrabutyl-ammonium chloride; In N,N-dimethyl-formamide; at -30 ℃; for 0.5h;

2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde; In N,N-dimethyl-formamide; at -30 ℃; for 1.5h;
DOI:10.1021/ol303291x