Apixaban Related Compound 4

Base Information

• Chemical Name: Apixaban Related Compound 4
• CAS No.: 99585-01-0
• Molecular Formula: C6H10Cl2O
• Molecular Weight: 169.051
• Mol file: 99585-01-0.mol

Synonyms:Apixaban Related Compound 4

Chemical Property of Apixaban Related Compound 4

Chemical Property:

• Boiling Point: 197.8±23.0 °C(Predicted)
• PSA: 17.07000
• Density: 1.143±0.06 g/cm3(Predicted)
• LogP: 2.54940

Purity/Quality:

≥99.0% ^*data from raw suppliers

5-Chlorohexanoylchloride 93% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 5-?Chloro-hexanoyl Chloride is an impurity of 5-chlorovaleroyl chloride.

Technology Process of Apixaban Related Compound 4

There total 3 articles about Apixaban Related Compound 4 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Hexanoyl chloride (142-61-0) → 4-chlorohexanoic chloride (99585-00-9) + 5-chloro-hexanoyl chloride (99585-01-0) + 6-chlorohexanoyl chloride (19347-73-0) + β-Chlor-caproylchlorid (90631-66-6)

Guidance literature:

With chlorine; In benzene; at 20 ℃; Product distribution; other solvents;

Reference yield:

chlorine (7782-50-5) + Hexanoyl chloride (142-61-0) → 4-chlorohexanoic chloride (99585-00-9) + 5-chloro-hexanoyl chloride (99585-01-0) + 6-chlorohexanoyl chloride (19347-73-0) + β-Chlor-caproylchlorid (90631-66-6)

Guidance literature:

at 20 ℃; im UV-Licht;

Reference yield:

chlorine (7782-50-5) + Hexanoyl chloride (142-61-0) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → 4-chlorohexanoic chloride (99585-00-9) + 5-chloro-hexanoyl chloride (99585-01-0) + 6-chlorohexanoyl chloride (19347-73-0) + β-Chlor-caproylchlorid (90631-66-6)

Guidance literature:

at 20 ℃; im UV-Licht;

DOI:10.1039/PS9590000109

upstream raw materials:

Hexanoyl chloride

chlorine

benzene

Downstream raw materials:

5-chloro-N,N-diphenylhexanamide

Refernces