1-CHLORO-5-(3,4-DIMETHOXYPHENYL)-5-OXOPENTANE

Base Information

• Chemical Name: 1-CHLORO-5-(3,4-DIMETHOXYPHENYL)-5-OXOPENTANE
• CAS No.: 33245-77-1
• Molecular Formula: C13H17ClO3
• Molecular Weight: 256.73
• Hs Code.: 2914700090
• Mol file: 33245-77-1.mol

Synonyms:1-CHLORO-5-(3,4-DIMETHOXYPHENYL)-5-OXOPENTANE

Chemical Property of 1-CHLORO-5-(3,4-DIMETHOXYPHENYL)-5-OXOPENTANE

Chemical Property:

• Vapor Pressure: 4.32E-06mmHg at 25°C
• Boiling Point: 383.7°C at 760 mmHg
• Flash Point: 152.8°C
• PSA: 35.53000
• Density: 1.116g/cm³
• LogP: 3.29560

Purity/Quality:

97% ^*data from raw suppliers

1-Chloro-5-(3,4-dimethoxyphenyl)-5-oxopentane 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-CHLORO-5-(3,4-DIMETHOXYPHENYL)-5-OXOPENTANE

There total 3 articles about 1-CHLORO-5-(3,4-DIMETHOXYPHENYL)-5-OXOPENTANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

1,2-dimethoxybenzene (91-16-7) + 5-Chlorovaleroyl chloride (1575-61-7) → 3,4-dimethoxy-ω-chlorovalerophenone (33245-77-1)

Guidance literature:

With aluminium trichloride; In nitromethane; at 25 ℃;

DOI:10.1007/BF02323383

Reference yield:

5-chloro-valeric acid (1119-46-6) → 3,4-dimethoxy-ω-chlorovalerophenone (33245-77-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 87 percent / SOCl₂ / dimethylformamide / 3 h / 75 °C

2: 69 percent / AlCl₃ / nitromethane / 25 °C

With aluminium trichloride; thionyl chloride; In nitromethane; N,N-dimethyl-formamide; 1: Substitution / 2: Acylation;

DOI:10.1007/BF02323383

Reference yield:

→ 3,4-dimethoxy-ω-chlorovalerophenone (33245-77-1)

Guidance literature:

Veratrol, AlCl3/ω-Chlorvaleroylchlorid;

upstream raw materials:

1,2-dimethoxybenzene

5-Chlorovaleroyl chloride

5-chloro-valeric acid

Refernces