4-Bromo-1-(triisopropylsilyl)-7-azaindole

Base Information

Chemical Name:4-Bromo-1-(triisopropylsilyl)-7-azaindole
CAS No.:640735-24-6
Molecular Formula:C16H25BrN2Si
Molecular Weight:353.377
Hs Code.:2933998090
European Community (EC) Number:813-580-2
Nikkaji Number:J1.994.513H
Mol file:640735-24-6.mol

Synonyms:640735-24-6;4-BROMO-1-(TRIISOPROPYLSILYL)-7-AZAINDOLE;4-BROMO-1-(TRIISOPROPYLSILYL)-1H-PYRROLO[2,3-B]PYRIDINE;1H-PYRROLO[2,3-B]PYRIDINE, 4-BROMO-1-[TRIS(1-METHYLETHYL)SILYL]-;4-bromo-1-[tris(propan-2-yl)silyl]-1H-pyrrolo[2,3-b]pyridine;(4-bromopyrrolo[2,3-b]pyridin-1-yl)-tri(propan-2-yl)silane;4-Bromo-1-1-(triisopropylsilyl)-7-azaindole;SCHEMBL794853;QSEMMUYKUYKNBI-UHFFFAOYSA-N;AMY34934;MFCD11616385;MFCD11616420;AKOS025289571;PB26669;AS-33627;SY098775;CS-0004172;FT-0746852;A855853;4-bromo-1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine

Suppliers and Price of 4-Bromo-1-(triisopropylsilyl)-7-azaindole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
4-Bromo-1-(triisopropylsilyl)-7-azaindole
1 g
$ 176.00

SynQuest Laboratories
4-Bromo-1-(triisopropylsilyl)-7-azaindole
500 mg
$ 104.00

Matrix Scientific
4-Bromo-1-1-(triisopropylsilyl)-7-azaindole
1g
$ 541.00

Matrix Scientific
4-Bromo-1-1-(triisopropylsilyl)-7-azaindole
5g
$ 1474.00

Labseeker
1H-PYRROLO[2,3-B]PYRIDINE,4-BROMO-1-[TRIS(1-METHYLETHYL)SILYL]- 95
10g
$ 2383.00

Labseeker
1H-PYRROLO[2,3-B]PYRIDINE,4-BROMO-1-[TRIS(1-METHYLETHYL)SILYL]- 95
5g
$ 1717.00

Labseeker
1H-PYRROLO[2,3-B]PYRIDINE,4-BROMO-1-[TRIS(1-METHYLETHYL)SILYL]- 95
1g
$ 1283.00

Crysdot
4-Bromo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine 95+%
1g
$ 446.00

Crysdot
4-Bromo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine 95+%
5g
$ 1443.00

Chemenu
4-bromo-1-[tris(propan-2-yl)silyl]-1H-pyrrolo[2,3-b]pyridine 95%+
1g
$ 322.00

Total 11 raw suppliers

Chemical Property of 4-Bromo-1-(triisopropylsilyl)-7-azaindole

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:343.363°C at 760 mmHg
PKA:4.43±0.30(Predicted)
Flash Point:161.461°C
PSA：17.82000
Density:1.197g/cm³
LogP:5.82240
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:352.09704
Heavy Atom Count:20
Complexity:311

Purity/Quality:

99%, ^*data from raw suppliers

4-Bromo-1-(triisopropylsilyl)-7-azaindole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)[Si](C(C)C)(C(C)C)N1C=CC2=C(C=CN=C21)Br

Technology Process of 4-Bromo-1-(triisopropylsilyl)-7-azaindole

There total 4 articles about 4-Bromo-1-(triisopropylsilyl)-7-azaindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 13154-24-0
triisopropylsilyl chloride

: 348640-06-2
4-bromo-7-azaindole

: 640735-24-6,934388-23-5
4-bromo-1-[tris(propan-2-yl)silyl]-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: With sodium hydride; In tetrahydrofuran; at 80 ℃; for 3h;
DOI:10.1021/ol036030z

Reference yield: 15.0%

: 13154-24-0
triisopropylsilyl chloride

: 640735-24-6,934388-23-5
4-bromo-1-[tris(propan-2-yl)silyl]-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: 4-bromo-7-azaindole; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.25h;

triisopropylsilyl chloride; In tetrahydrofuran; at 80 ℃; for 3.5h;

Reference yield:

: 55052-24-9
1H-Pyrrolo[2,3-b]pyridine-7-oxide

: 640735-24-6,934388-23-5
4-bromo-1-[tris(propan-2-yl)silyl]-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 54 percent / tetramethylammonium bromide; methanesulfonic anhydride / dimethylformamide / 4 h / 0 - 23 °C

2: 99 percent / sodium hydride / tetrahydrofuran / 3 h / 80 °C

With tetramethylammonium bromide; sodium hydride; Methanesulfonic anhydride; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/ol036030z