Flunixin meglumine

Base Information

• Chemical Name: Flunixin meglumine
• CAS No.: 42461-84-7
• Molecular Formula: C₇H₁₇NO₅*C₁₄H₁₁F₃N₂O₂
• Molecular Weight: 491.464
• Hs Code.: 29339900
• European Community (EC) Number: 255-836-0
• NSC Number: 759583
• UNII: 8Y3JK0JW3U
• Wikidata: Q27145782
• NCI Thesaurus Code: C76804
• RXCUI: 25122
• ChEMBL ID: CHEMBL1733447
• Mol file: 42461-84-7.mol

Synonyms:Banamine;finadyne;flunixin meglumine;Sch 14714 meglumine

Chemical Property of Flunixin meglumine

Chemical Property:

• Appearance/Colour: off-white powder
• Vapor Pressure: 2.08E-06mmHg at 25°C
• Melting Point: 136-138 °C
• Boiling Point: 378.7 °C at 760 mmHg
• Flash Point: 182.8 °C
• PSA: 175.40000
• Density: 1.403 g/cm3
• LogP: 0.95620
• Storage Temp.: 0-6°C
• Solubility.: H2O: freely soluble
• Water Solubility.: soluble
• Hydrogen Bond Donor Count: 8
• Hydrogen Bond Acceptor Count: 13
• Rotatable Bond Count: 9
• Exact Mass: 491.18793473
• Heavy Atom Count: 34
• Complexity: 510

Purity/Quality:

Above 99% ^*data from raw suppliers

Flunixin Meglumine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=C(C=CC=C1NC2=C(C=CC=N2)C(=O)O)C(F)(F)F.CNCC(C(C(C(CO)O)O)O)O
• Isomeric SMILES: CC1=C(C=CC=C1NC2=C(C=CC=N2)C(=O)O)C(F)(F)F.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
• Uses: dental carries prophylactic Flunixin meglumine has been used as a nonsteroidal anti-inflammatory drug standard in electrospray ionization mass spectrometry (LC-ESI/MS). Cyclooxigenase inhibitor. Anti-inflammatory; analgesic; antipyretic.

Technology Process of Flunixin meglumine

There total 2 articles about Flunixin meglumine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-deoxy-1-(methylamino)-D-glucitol (6284-40-8,97780-33-1) + flunixin (38677-85-9) → flunixin Meglumine (42461-84-7)

Guidance literature:

With maltodextrin; In isopropyl alcohol; Reagent/catalyst; Reflux;

Reference yield:

→ flunixin Meglumine (42461-84-7)

Guidance literature:

upstream raw materials:

1-deoxy-1-(methylamino)-D-glucitol

flunixin

Refernces

• 1、 -. "Process for preparing flunixin and intermediates thereof". . . Retrieved 2008/06/13.