THYMIDINE, METHYL-D3

Base Information

Chemical Name:THYMIDINE, METHYL-D3
CAS No.:74848-84-3
Molecular Formula:C10H11D3N2O5
Molecular Weight:245.208
Hs Code.:
Mol file:74848-84-3.mol

Synonyms:THYMIDINE, METHYL-D3;1-(2-Deoxy-b-D-ribofuranosyl)-5-methyluracil-d3;Thymine-2-desoxyriboside-d3;1-(2-Deoxy--D-ribofuranosyl)-5-methyluracil-d3;ThyMidine-d3;[Methyl-2H3]thyMidine

Suppliers and Price of THYMIDINE, METHYL-D3

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Thymidine, Methyl-d3
2.5mg
$ 403.00

TRC
Thymidine-d3
2.5mg
$ 135.00

Medical Isotopes, Inc.
D3-Thymidine
5 mg
$ 635.00

Biosynth Carbosynth
D3-Thymidine
10 mg
$ 367.50

Biosynth Carbosynth
D3-Thymidine
5 mg
$ 235.00

Biosynth Carbosynth
D3-Thymidine
2 mg
$ 125.00

Biosynth Carbosynth
D3-Thymidine
1 mg
$ 75.00

Biosynth Carbosynth
D3-Thymidine
25 mg
$ 600.00

American Custom Chemicals Corporation
1-(2-DEOXY-BETA-D-RIBOFURANOSYL)-5-METHYLURACIL-D3 95.00%
100MG
$ 1593.90

American Custom Chemicals Corporation
1-(2-DEOXY-BETA-D-RIBOFURANOSYL)-5-METHYLURACIL-D3 95.00%
10MG
$ 704.55

Total 6 raw suppliers

Chemical Property of THYMIDINE, METHYL-D3

Chemical Property:

Melting Point:184-184°C
PSA：104.55000
Density:1.47g/cm³
LogP:-1.51430
Storage Temp.:-20°C Freezer
Solubility.:DMSO (Slightly), Methanol (Slightly), Water (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

Thymidine, Methyl-d3 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Thymidine-α,α,α-D3 is the labeled version of Thymidine (T412000), constituent of deoxyribonucleic acid.

Technology Process of THYMIDINE, METHYL-D3

There total 1 articles about THYMIDINE, METHYL-D3 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 41251-37-0
methyl-d3-magnesium iodide

: 148134-86-5
2'-deoxy-3',5'-bis(O-tert-butyldimethylsilyl)-5-iodouridine

: 74848-84-3
2'-deoxy-5-(trideuteriomethyl)uridine

Guidance literature:: methyl-d3-magnesium iodide; 2'-deoxy-3',5'-bis(O-tert-butyldimethylsilyl)-5-iodouridine; In tetrahydrofuran; diethyl ether; at 0 ℃; for 0.5h;

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; copper(I) bromide; In tetrahydrofuran; diethyl ether; at 20 ℃;

With pyridine; pyridine hydrogenfluoride; In tetrahydrofuran; diethyl ether; ethyl acetate; at 20 ℃; for 21h;
DOI:10.1021/ja403229y

Reference yield:

: 74848-84-3
2'-deoxy-5-(trideuteriomethyl)uridine

: C₄₃H₄₄⁽²⁾H₃N₄O₁₄P

Guidance literature:: Multi-step reaction with 4 steps

1: 1H-imidazole / N,N-dimethyl-formamide / 24 h / 0 °C / Inert atmosphere

2: pyridine / 18 h / 20 °C / Inert atmosphere

3: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 12 h / 20 °C / Inert atmosphere

4: pivaloyl chloride / pyridine / 0.25 h / Inert atmosphere

With pyridine; 1H-imidazole; tetrabutyl ammonium fluoride; pivaloyl chloride; acetic acid; In tetrahydrofuran; pyridine; N,N-dimethyl-formamide;
DOI:10.1002/anie.201005228

Reference yield:

: 74848-84-3
2'-deoxy-5-(trideuteriomethyl)uridine

: 1263481-73-7
C₄₃H₄₄⁽²⁾H₃N₄O₁₅P

Guidance literature:: Multi-step reaction with 5 steps

1: 1H-imidazole / N,N-dimethyl-formamide / 24 h / 0 °C / Inert atmosphere

2: pyridine / 18 h / 20 °C / Inert atmosphere

3: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 12 h / 20 °C / Inert atmosphere

4: pivaloyl chloride / pyridine / 0.25 h / Inert atmosphere

5: water; iodine / tetrahydrofuran; pyridine / 0.17 h / Inert atmosphere

With pyridine; 1H-imidazole; tetrabutyl ammonium fluoride; water; iodine; pivaloyl chloride; acetic acid; In tetrahydrofuran; pyridine; N,N-dimethyl-formamide;
DOI:10.1002/anie.201005228