95306-84-6

Basic information

• Product Name: 1H-Indole-2-carboxylic acid, 5-chloro-1-(phenylmethyl)-, ethyl ester
• CAS NO: 95306-84-6
• Molecular Formula: C18H16ClNO2
• Molecular Weight: 313.784
• Mol File: 95306-84-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1H-Indole-2-carboxylic acid, 5-chloro-1-(phenylmethyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-2-carboxylic acid, 5-chloro-1-(phenylmethyl)-, ethyl ester(95306-84-6)
• EPA Substance Registry System: 1H-Indole-2-carboxylic acid, 5-chloro-1-(phenylmethyl)-, ethyl ester(95306-84-6)

Safety Data

• Hazardous Substances Data: 95306-84-6(Hazardous Substances Data)

Upstream product

• 4792-67-0 5-chloro-indole-2-carboxylic acid ethyl ester 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 

Downstream Products

• 1026645-16-8 5-chloro-1-benzylindole-2-carboxylic acid 
• 934615-93-7 tert-Butyl 3-(1-benzyl-5-chloro-1H-indol-2-yl)-3-oxopropanoate 
• 480450-91-7 ethyl 1-benzyl-5-chloro-3-fluoroindole-2-carboxylate 
• 4792-67-0 5-chloro-indole-2-carboxylic acid ethyl ester 

Relevant articles and documents

The discovery of novel indole-2-carboxamides as cannabinoid CB1 receptor antagonists

The discovery and structure-activity relationship of a novel series of indole-2-carboxamide antagonists of the cannabinoid CB1 receptor is disclosed. Compound 26i was found to be a high potency, selective cannabinoid CB1 antagonist.

Acyl indoles, compositions containing such compounds and methods of use

The present invention relates to substituted indoles, compositions containing such compounds and methods of treatment The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes mellitus and related conditions.

Diamine derivatives

A compound represented by the general formula (1): Q1-Q2-T0-N(R1)-Q3-N(R2)-T1-Q4??(1) wherein R1 and R2 are hydrogen atoms or the like; Q1 is a saturated or unsaturated, 5- or 6-membered cyclic hydrocarbon group which may be substituted, or the like; Q2 is a single bond or the like; Q3 is a group in which Q5 is an alkylene group having 1 to 8 carbon atoms, or the like; and T0 and T1 are carbonyl groups or the like; a salt thereof, a solvate thereof, or an N-oxide thereof. The compound is useful as an agent for preventing and/or treating cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism, Buerger's disease, deep venous thrombosis, disseminated intravascular coagulation syndrome, thrombus formation after valve or joint replacement, thrombus formation and reocclusion after angioplasty, systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), thrombus formation during extracorporeal circulation, or blood clotting upon blood drawing.