Pertechnetate Tc-99m

Base Information

• Chemical Name: Pertechnetate Tc-99m
• CAS No.: 23288-61-1
• Molecular Formula: O₄Tc
• Molecular Weight: 161.905
• UNII: PPP8783IQ1
• Wikidata: Q27286696
• Mol file: 23288-61-1.mol

Synonyms:Pertechnetate Tc-99m;PPP8783IQ1;PERTECHNETATE TC-99M ANION;PERTECHNETATE (99TCO41-);TETRAOXOTECHNETATE(1-)-99TC;TECHNETATE (99TCO41-), (T-4)-;TECHNETIUM (99MTC) PERTECHNETATE [WHO-DD];Q27286696;23288-61-1

Chemical Property of Pertechnetate Tc-99m

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 68.28000
• Density: g/cm³
• LogP: -0.47770
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 162.885908
• Heavy Atom Count: 5
• Complexity: 95.8

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: [O-][Tc](=O)(=O)=O
• Isomeric SMILES: [O-][99Tc](=O)(=O)=O

Technology Process of Pertechnetate Tc-99m

There total 40 articles about Pertechnetate Tc-99m which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

fac-triaquatricarbonyltechnetium-99m(1+) + Na(1+)*C2B9H11C6H5(1-)=NaC2B9H11C6H5 → 99mtechnetium pertechnetate (23288-61-1) + Na(1+)*C2B9H10C6H5(99)Tc(CO)3(1-)=NaC2B9H10C6H5(99)Tc(CO)3 (1153642-28-4)

Guidance literature:

In ethanol; water; other Radiation; (Ar); addn. of Tc complex to a soln. of boron compd. in aq. ethanol (10%vol.), microwave heating for 5 min at 180°C; C18 solid phase extn. cartridge, flushing with H2O, elution with acetonitrile, identified by radio-HPLC (Nucleosil C18 column, tetraethylammonium phosphate in methanol 100% to 0% 0-22 min, 0-100% 22-30 min);

DOI:10.1021/om8011807

Reference yield: 65.0%

tetrabutylammonium [(99g)Tc]tetrachlorooxotechnetate(V) + 2-hydroxymethyl-2-dimethylamino-1,3-propanediol methiodide (102722-08-7) → 99mtechnetium pertechnetate (23288-61-1) + ((99)Tc(N(CH3)3C(CH2O)3)2)

Guidance literature:

With (C₄H₉)4NOH; In isopropyl alcohol; byproducts: polymeric compounds; addn. of Bu4NOH in 2-propanol to Bu4N((99)TcOCl4) and ((CH3)3NC(CH2OH)3)I under Ar, treating the mixt. in an ultrasonic vibrator, color changes to red brown; controlling by paper chromy.;

Reference yield: 64.0%

fac[99mTc(OH2)3(CO)3]+ (524744-56-7,524730-33-4) + C2B9H11(CH2CH2COOH)(1-) + sodium fluoride (7681-49-4) → 3,1,2-[Na][Tc(CO)3(HO2CCH2CH2C2B9H10)] + pertechnetate anion (23288-61-1)

Guidance literature:

In water; other Radiation; using microwaves for 15 min; solid-phase extn.;

DOI:10.1021/ic0605928

upstream raw materials:

oxopentachlorotechnetate(V)^(2-)

nitric acid

technetium (IV)

K⁽¹⁺⁾*{TcF₆}^(1-)=K{TcF₆}

Downstream raw materials:

technetium (IV)

hexakis(ethyl isocyanoacetato)technetium(I) tetraphenylboranate

diquinonediimine