D-Mannose-1-13C

Base Information

• Chemical Name: D-Mannose-1-13C
• CAS No.: 70849-31-9
• Molecular Formula: C6H12O6
• Molecular Weight: 181.147
• DSSTox Substance ID: DTXSID50484452
• Nikkaji Number: J2.130.709B
• Mol file: 70849-31-9.mol

Synonyms:D-Mannose-1-13C;70849-31-9;(3S,4S,5S,6R)-6-(hydroxymethyl)(213C)oxane-2,3,4,5-tetrol;DTXSID50484452;D-Mannose-1-13C, 99 atom % 13C;99 atom% 13C pound>>99% pound CP pound(c)

Chemical Property of D-Mannose-1-13C

Chemical Property:

• Melting Point: 133 °C(lit.)
• PSA: 110.38000
• Density: 1.732g/cm³
• LogP: -3.22140
• XLogP3: -2.6
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 181.06674293
• Heavy Atom Count: 12
• Complexity: 151

Purity/Quality:

95% ^*data from raw suppliers

D-Mannose-1-13C ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C1C(C(C(C(O1)O)O)O)O)O
• Isomeric SMILES: C([C@@H]1[C@H]([C@@H]([C@@H]([13CH](O1)O)O)O)O)O
• Uses: (D-Mannose-1-13C) D-Mannose is a carbohydrate that is important in the glycosylation of molecules in a variety of cellular processes. It is involved in N and O glycosylation of bovine why protein products, used in infant formulas. It is also responsible for the O-glycosylation of the T helper cell-derived cytokine interlukin-17A, an important cell-signaling molecule. This is the labeled analog.

Technology Process of D-Mannose-1-13C

There total 2 articles about D-Mannose-1-13C which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

D-Arabinose (10323-20-3) + potassium [13C]cyanide → [1-13C]D-glucose (40762-22-9,478519-02-7) + <1-13C>-D-mannose (70849-31-9,478519-02-7)

Guidance literature:

With hydrogen; Pd-BaSO₄; Multistep reaction; 1.) pH 7.2-7.5;

DOI:10.1021/ja00246a001

Reference yield:

D-<2-13C>glucose (70849-16-0,83379-35-5,83379-36-6,70849-17-1,478529-73-6) → <1-13C>-D-mannose (70849-31-9,478519-02-7)

Guidance literature:

With sodium vanadate; sulfuric acid; oxygen; In water; at 100 ℃;

DOI:10.1039/c8cp02352b

Reference yield:

<1-13C>-D-mannose (70849-31-9,478519-02-7) → [1-13C]D-glucose (40762-22-9,478519-02-7) + D-<2-13C>glucose (70849-16-0,83379-35-5,83379-36-6,70849-17-1,478529-73-6)

Guidance literature:

molybdenum(VI) oxide; In water; at 92 ℃;

DOI:10.1016/S0008-6215(00)90268-4

upstream raw materials:

D-Arabinose

D-<2-13C>glucose

Downstream raw materials:

[1-13C]D-glucose

D-<2-13C>glucose

<1-13C>Mannitol