D-Glucose-1-13C

Base Information

• Chemical Name: D-Glucose-1-13C
• CAS No.: 40762-22-9
• Molecular Formula: C6H12 O6
• Molecular Weight: 181.147
• Hs Code.: 28459000
• Mol file: 40762-22-9.mol

Synonyms:D-[1-13C]Glucose;Glucose-1-13C; [1-13C]-D-Glucose; [1-13C]D-Glucose

Chemical Property of D-Glucose-1-13C

Chemical Property:

• Melting Point: 150-152 °C(lit.)
• PSA: 110.38000
• LogP: -3.22140
• Storage Temp.: Room Temperature
• Solubility.: Methanol (Slightly, Heated), Water

Purity/Quality:

99% ^*data from raw suppliers

D-Glucose-1-13C ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: D-GLUCOSE-1-13C is a simple sugar that is present in plants. A monosaccharide that may exist in open chain or cyclic conformation if in solution. It plays a vital role in photosynthesis and fuels the energy required for cellular respiration. D-Glucose is used in various metabolic processes including enzymic synthesis of cyclohexyl-α and β-D-glucosides. D-GLUCOSE-1-13C Can also be used as a diagnostic tool in detection of type 2 diabetes mellitus and potentially Huntington's disease through analysis of blood-glucose in type 1 diabetes mellitus. D-Glucose-1-13C can be used:To predict the primary reaction mechanism in pyrolysis of glucose.To study C?C bond cleavage mechanism in the conversion of labeled glucose into alkanediols using Ni?MgO?ZnO catalyst.In tracer enrichment determination in blood plasma using high-resolution mass spectrometry.

Technology Process of D-Glucose-1-13C

There total 3 articles about D-Glucose-1-13C which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

D-Arabinose (10323-20-3) + potassium [13C]cyanide → [1-13C]D-glucose (40762-22-9,478519-02-7) + <1-13C>-D-mannose (70849-31-9,478519-02-7)

Guidance literature:

With hydrogen; Pd-BaSO₄; Multistep reaction; 1.) pH 7.2-7.5;

DOI:10.1021/ja00246a001

Reference yield:

<1-13C>-D-mannose (70849-31-9,478519-02-7) → [1-13C]D-glucose (40762-22-9,478519-02-7) + D-<2-13C>glucose (70849-16-0,83379-35-5,83379-36-6,70849-17-1,478529-73-6)

Guidance literature:

molybdenum(VI) oxide; In water; at 92 ℃;

DOI:10.1016/S0008-6215(00)90268-4

Reference yield:

α- and β-D-<1-13C>mannose (40010-55-7,40010-56-8,56746-22-6,60821-16-1,60821-17-2,60821-20-7,60821-21-8) → [1-13C]D-glucose (40762-22-9,478519-02-7) + <1-13C>-D-fructose (108311-21-3)

Guidance literature:

at 25 ℃; mildly basic condition; equilibrium;

DOI:10.1016/S0008-6215(00)90019-3

upstream raw materials:

D-Arabinose

<1-13C>-D-mannose

α- and β-D-<1-13C>mannose

Downstream raw materials:

D-(1-13C)glucitol

C₁-¹³C-tri-O-benzyl-D-glucal

2,3,4,6,2',3',4',6'-octa-O-benzyl-(1,1'-13C)-α,β-trehalose

2,3,4,6,2',3',4',6'-octa-O-benzyl-(1,1'-13C)-α,α-trehalose

Refernces

• 1、 King-Morris, Melinda J.,Serianni, Anthony S.. "HYDROXIDE-CATALYZED ISOMERIZATION OF D-(1-13C)MANNOSE: EVIDENCE FOR THE INVOLVEMENT OF 3,4-ENEDIOLS". . p. 29 - 36. Retrieved 2007/10/02.