10323-20-3Relevant articles and documents
EFFECT OF PRESSURE ON THE RATES OF OXIDATION OF MONOSACCHARIDES WITH VANADIUM(V)
Virtanen, Pentti O. I.,Koukkanen, Toivo,Rauma, Touko
, p. 29 - 34 (1988)
The effect of pressure on the rates of the oxidation of D-galactose, D-glucose, D-mannose, D-fructose, L-sorbose, L-arabinose, D-ribose, and D-xylose with vanadium(V) in perchloric acid was studied.The activation volumes for the monosaccharides were positive and approximately equal (7.5+/-1.3 mL*mol-1), with negligible dependence on pressure up to 200 MPa at least.These observations indicate the same mechanism for the formation of the activated complexes.A mechanism involving formation of a radical by hydrogen atom transfer in the rate-determining decomposition of a monosaccharide-vanadium(V) complex is proposed.
Isolation and structure determination of acetylated triterpenoid saponins from the seeds of Centratherum anthelminticum
Mehta,Mehta, Darshana,Itoriya, Amrita
, p. 120 - 130 (2010)
Phytochemical investigation of Centratherum anthelminticum seeds resulted in the isolation of two novel glycosides. The pentacyclic triterpenoid saponins were shown to contain hederagenin and sugar residues forming two glycosyl chains. The structural analysis of its acetylated derivative was determined using a combination of homo- (1D 1H NMR, 13C NMR and 13C NMR-DEPT) and heteronuclear 2D NMR techniques ( 1H-1H-COSY, total correlated spectroscopy (TOCSY), heteronuclear multiple quantum coherence (HMQC)), heteronuclear multiple bond correlation (HMBC) and chemical methods. The structure of the saponins were established to be 3-O-[β-D-glucopyranosyl-(1 → 2)- α- L-rhamnopyranosyl-(1 → 2)-α - L-arabinopyranosyl]-28-O-[β-D- xylopyranosyl-(1 → 4)- α - L-rhamnopyranosyl-(1 → 3)- β - D-glucopyranosyl]-23-hydroxyolean-12-en-28-oic acid and 3-O-[β-D- glucopyranosyl-(1 → 2)- α - L-rhamnopyranosyl-(1 → 2)- α - L-arabinopyranosyl]-28-O-[β-D-glucoyranosyl-(1 → 3)- β - D-glucopyranosyl]-23-hydroxyolean-12-en-28-oic acid. Different extracts and compounds were also tested for antifilarial and antimicrobial activities. Methanolic, acetone and aqueous extracts of seeds exhibited some pronounced pharmacological activity under study.
Extraction, purification, characterization and hypoglycemic activity of a polysaccharide isolated from the root of Ophiopogon japonicus
Chen, Xiaoming,Jin, Jing,Tang, Jia,Wang, Zhongfu,Wang, Junjun,Jin, Liqin,Lu, Jianxin
, p. 749 - 754 (2011)
In this research, a water-soluble polysaccharide (OJP1) extracted with hot water from the roots of Ophiopogon japonicus which is a traditional Chinese medicinal herb was precipitated with 95% ethanol and purified by DEAE-52 cellulose anion-exchange and Sephadex G-100 gel filtration chromatography. The high performance gel permeation chromatography (HPGPC) analysis showed that the average molecular weight (Mw) of OJP1 was 35.2 kDa. Monosaccharides analysis revealed that the OJP1 is composed of Ara, Glc, Gal with a relative molar ratio of 1:16:8. Pharmaceutical experiments showed OJP1 can significantly reduce blood glucose level, increase the insulin level and remediating destruction of pancreatic islets in STZ-induced diabetic rats compared with the diabetic control group. The study shows that OJP1 has an anti-diabetic effect on STZ-induced diabetic rats, and has potential use as an anti-diabetic agent. Copyright
Antibacterial Activity of a New Flavone Glycoside from the Stems of Holmskioldia sanguinea Retz.
Yadava,Raghuvansi, Jyotsna
, p. 1815 - 1818 (2019)
A new flavone glycoside was isolated from ethanolic extract of stem parts of Holmskioldia sanguinea Retz. Its structure was characterized as 3,4′-dihydroxy-5,7-dimethoxyflavone-3-O-β-D-galactopyranosyl(1→4)-O-β-D-arabinopyranosyl-4′-O-α-L-rhamnopyranoside (1) by colour reactions, chemical degradation and spectroscopic analysis. Antibacterial activity of compound 1 was evaluated against various Gram positive and Gram negative bacteria showing a significant effects.
A new kaempferol trioside from Farsetia aegyptia
Marzouk,Kawashty,Saleh,Al-Nowaihi, Abdel Salam M.
, p. 483 - 486 (2009)
A new kaempferol trioside, kaempferol-3-O-(2-α-L-arabinopyranosyl)- α-L-rhamnopyranoside-7-O-α-L-rhamnopyranoside, along with eight known flavonoid compounds were isolated from the methanolic extract of Farsetia aegyptia Turra. growing in Egypt. The struc
Kaempferol glycosides from Lobularia maritima and their potential role in plant interactions
Fiorentino, Antonio,Ricci, Andreina,D'Abrosca, Brigida,Golino, Annunziata,Izzo, Angelina,Pascarella, Maria Teresa,Piccolella, Simona,Esposito, Assunta
, p. 204 - 217 (2009)
Six kaempferol glycosides, four of them characterized for the first time, were isolated from the leaf extract of Lobularia maritima. The structural elucidation was performed by a combined approach using Electrospray-Ionization Triple-Quadrupole Mass-Spect
Selective electrocatalytic oxidation of sorbitol to fructose and sorbose
Kwon, Youngkook,De Jong, Ed,Van Der Waal, Jan Kees,Koper, Marc T. M.
, p. 970 - 973 (2015)
A new electrocatalytic method for the selective electrochemical oxidation of sorbitol to fructose and sorbose is demonstrated by using a platinum electrode promoted by p-block metal atoms. By the studying a range of C4, C5 and C6 polyols, it is found that the promoter interferes with the stereochemistry of the polyol and thereby modifies its reactivity.
Antitumor and immunomodulatory activities of a polysaccharide from Artemisia argyi
Bao, Xiaoli,Yuan, Huihui,Wang, Chengzhong,Liu, Jinjin,Lan, Minbo
, p. 1236 - 1243 (2013)
A water-soluble polysaccharide (FAAP-02), composed of N-acetyl-d- glucosamine, glucose, mannose, galactose, rhamnose arabinose, xylose and ribose, with an average molecular weight of 5169 Da, was isolated from Artemisia argyi. The antitumor and immunomodulatory activities of FAAP-02 were evaluated in Sarcoma 180 (S180) tumor-bearing mice by intraperitoneal administration. As a result, FAAP-02 significantly inhibited the growth of the S180 transplanted tumors and prolonged the survival time of the tumor-bearing mice. Moreover, FAAP-02 could obviously increase the thymus and spleen indices, the levels of serum Interleukin 2 (IL-2), Interleukin 6 (IL-6), Interleukin 12 (IL-12) and tumor necrosis factor- α (TNF-α) and the expression of CD4+ and CD8+ splenic T lymphocytes which were suppressed by the transplanted tumor or/and 5-fluorouracil (5-FU) in the mice. These results indicated that the antitumor activity of FAAP-02 might be associated with its immunostimulatory effects.
Four new triterpenoids isolated from the resin of Garcinia hanburyi
Wang, Hong-Min,Liu, Qun-Fang,Zhao, Yi-Wu,Liu, Shuang-Zhu,Chen, Zhen-Hua,Zhang, Ru-Jun,Wang, Zhen-Zhong,Xiao, Wei,Zhao, Wei-Min
, p. 20 - 28 (2014)
Four new triterpenoids, 2-O-acetyl-3-O-(4′-O-acetyl)-α-l- arabinopyranosylmaslinic acid (1), 2-O-acetyl-3-O-(3′-O-acetyl)-α-l- arabinopyranosylmaslinic acid (2), 2-O-acetyl-3-O-(3′,4′-O-diacetyl) -α-l-arabinopyranosylmaslinic acid (3), and 3-O-(3′-O-acety
Adjuvant effect of Atractylodis macrocephalae Koidz. Polysaccharides on the immune response to foot-and-mouth disease vaccine
Xie, Feng,Li, Yutao,Su, Fei,Hu, Songhua
, p. 1713 - 1719 (2012)
Present study was designed to investigate the polysaccharide (RAMPS) extracted from the rhizome of Atractylodis macrocephalae Koidz. (RAM) for its effect on the immune responses to foot-and-mouth (FMD) vaccine. Thirty-five ICR mice were randomly distributed into 5 groups with 7 mice in each. After oral administration of RAMPS for 4 days at a dose of 0, 0.025, 0.05, 0.1 g or 0.25 g of RAM, respectively, the animals were immunized twice with FMD vaccine at 2-week intervals. Three weeks later, serum IgG, IFN-γ/IL-5, splenocyte proliferation, and mRNA expression of cytokines by splenocytes were measured. Results indicated that RAMPS and RAM significantly enhanced IgG titers, IgG subclasses, IFN-γ, IL-5 and the splenocyte proliferations stimulated by concanavalin A, lipopolysacharide, and FMDV (P 0.05). Therefore, RAMPS and RAM increased both cellular and humoral immune responses to vaccination, and may have a potential as an oral adjuvant to improve vaccination.
