Chloroacetyl-DL-serine

Base Information

• Chemical Name: Chloroacetyl-DL-serine
• CAS No.: 67206-28-4
• Molecular Formula: C5H8ClNO4
• Molecular Weight: 181.576
• European Community (EC) Number: 679-587-6
• NSC Number: 163127
• Mol file: 67206-28-4.mol

Synonyms:CHLOROACETYL-DL-SERINE;67206-28-4;2-(2-chloroacetamido)-3-hydroxypropanoic acid;2-[(2-chloroacetyl)amino]-3-hydroxypropanoic acid;80174-65-8;N-Chloroacetyl-DL-serine;n-(chloroacetyl)serine;NSC163127;ClAc-DL-Ser-OH;Chloracetyl-D,L-serin;SCHEMBL11303240;MFCD00020416;AKOS006228385;NSC-163127;BS-23729;CS-0206541;D89198

Chemical Property of Chloroacetyl-DL-serine

Chemical Property:

• Vapor Pressure: 8.11E-12mmHg at 25°C
• Melting Point: 122 °C
• Boiling Point: 493.7oC at 760 mmHg
• Flash Point: 252.4oC
• PSA: 86.63000
• Density: 1.501g/cm3
• LogP: -0.82220
• Storage Temp.: Store at 0°C
• Water Solubility.: very faint turbidity
• XLogP3: -0.9
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 181.0141854
• Heavy Atom Count: 11
• Complexity: 161

Purity/Quality:

98% ^*data from raw suppliers

Chloroacetyl-dl-serine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C(=O)O)NC(=O)CCl)O

Technology Process of Chloroacetyl-DL-serine

There total 3 articles about Chloroacetyl-DL-serine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

O-chloroacetyl-DL-serine (89416-21-7) → N-chloroacetyl-DL-serine (67206-28-4)

Guidance literature:

With sodium hydroxide;

DOI:10.1139/v61-329

Reference yield:

serin (302-84-1,83245-15-2) + chloroacetyl chloride (79-04-9) → N-chloroacetyl-DL-serine (67206-28-4)

Guidance literature:

With sodium hydroxide;

Reference yield:

→ N-chloroacetyl-DL-serine (67206-28-4)

Guidance literature:

DL-<1-¹⁴C>-Serin, 1. Chloressigsaeureanhydrid, wss. 1n-KOH, 5grad, 2 h, 2. Ionenaustauscher;

upstream raw materials:

serin

chloroacetyl chloride

O-chloroacetyl-DL-serine

Downstream raw materials:

N-glycyl-serine methyl ester

3-hydroxymethyl-2,5-diketopiperazine

N-glycylserine