Thieno[3,4-d]pyrimidine-2,4(1H,3H)-dione, 5,7-dihydro-

Base Information

Chemical Name:Thieno[3,4-d]pyrimidine-2,4(1H,3H)-dione, 5,7-dihydro-
CAS No.:5719-34-6
Molecular Formula:C₆H₆N₂O₂S
Molecular Weight:170.192
Hs Code.:2934999090
European Community (EC) Number:669-164-4
Mol file:5719-34-6.mol

Synonyms:5719-34-6;Thieno[3,4-d]pyrimidine-2,4(1H,3H)-dione, 5,7-dihydro-;5h,7h-Thieno[3,4-d]pyrimidine-2,4-diol;5,7-Dihydrothieno[3,4-d]pyrimidine-2,4-diol;5,7-dihydro-1H-thieno[3,4-d]pyrimidine-2,4-dione;5,7-dihydrothieno[3,4-d]pyrimidine-2,4(1h,3h)-dione;5,7-DIHYDROTHIENO(3,4-D)PYRIMIDINE-2,4-DIOL;SCHEMBL1620313;SCHEMBL13982645;RCZJDYOOUXZORM-UHFFFAOYSA-N;AKOS024321052;CS-0246928;EN300-3477314;Z1255490035;thieno[3,4-d]pyrimidine-2,4-(1H, 3H, 5H, 7H)-dione

Suppliers and Price of Thieno[3,4-d]pyrimidine-2,4(1H,3H)-dione, 5,7-dihydro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5,7-DIHYDROTHIENO-(3,4-D)PYRIMIDINE-2,4-DIOL 95.00%
5MG
$ 496.93

Total 12 raw suppliers

Chemical Property of Thieno[3,4-d]pyrimidine-2,4(1H,3H)-dione, 5,7-dihydro-

Chemical Property:

Melting Point:300 °C
PKA:9.88±0.20(Predicted)
PSA：91.54000
Density:1.58±0.1 g/cm3(Predicted)
LogP:0.63460
XLogP3:-0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:170.01499861
Heavy Atom Count:11
Complexity:272

Purity/Quality:

LC>99% ^*data from raw suppliers

5,7-DIHYDROTHIENO-(3,4-D)PYRIMIDINE-2,4-DIOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2=C(CS1)NC(=O)NC2=O

Technology Process of Thieno[3,4-d]pyrimidine-2,4(1H,3H)-dione, 5,7-dihydro-

There total 6 articles about Thieno[3,4-d]pyrimidine-2,4(1H,3H)-dione, 5,7-dihydro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 5719-20-0
5H,7H-2-ethylthiodihydrothieno<3,4-d>pyrimidin-4-one

: 5719-34-6
5H,7H-2-dihydrothieno<3,4-d>pyrimidine-2,4-dione

Guidance literature:: With hydrogenchloride; water; acetic acid; for 5h; Reflux;
DOI:10.1021/jm800865a

Reference yield:

: 2689-68-1,99328-39-9
methyl 4-oxotetrahydrothiophene-3-carboxylate

: 5719-34-6
5H,7H-2-dihydrothieno<3,4-d>pyrimidine-2,4-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / aq. Na₂CO₃ / 12 h / Ambient temperature

2: 65 percent / AcOH, conc. HCl / H₂O / 0.33 h / Heating; Irradiation

With hydrogenchloride; sodium carbonate; acetic acid; In water;

Reference yield:

: 7400-45-5
dimethyl-3-thiaadipate

: 5719-34-6
5H,7H-2-dihydrothieno<3,4-d>pyrimidine-2,4-dione

Guidance literature:: Multi-step reaction with 3 steps

1: lithium methanolate / toluene / 18.5 h / 70 - 110 °C

2: sodium carbonate / water / 20 °C / Darkness

3: water; hydrogenchloride; acetic acid / Reflux

With hydrogenchloride; lithium methanolate; water; sodium carbonate; acetic acid; In water; toluene;