2-methoxy-5-[3-[(phenylmethyl)amino]propyl]-

Base Information

Chemical Name:2-methoxy-5-[3-[(phenylmethyl)amino]propyl]-
CAS No.:253135-13-6
Molecular Formula:C17H21NO2
Molecular Weight:271.35
Hs Code.:
Mol file:253135-13-6.mol

Synonyms:2-methoxy-5-[3-[(phenylmethyl)amino]propyl]-;N-benzyl-3-(3-hydroxy-4-methoxyphenyl)propylamine

Suppliers and Price of 2-methoxy-5-[3-[(phenylmethyl)amino]propyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 2-methoxy-5-[3-[(phenylmethyl)amino]propyl]-

Chemical Property:

Melting Point:115 - 117 °C
PSA：41.49000
LogP:3.51410

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 2-methoxy-5-[3-[(phenylmethyl)amino]propyl]-

There total 7 articles about 2-methoxy-5-[3-[(phenylmethyl)amino]propyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 253135-11-4
N-benzyl-3-(3-hydroxy-4-methoxyphenyl)propanamide

: 253135-13-6
N-benzyl-3-(3-hydroxy-4-methoxyphenyl)propylamine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 16h; Reflux;
DOI:10.1002/anie.201302530

Reference yield:

: 621-59-0
isovanillin

: 253135-13-6
N-benzyl-3-(3-hydroxy-4-methoxyphenyl)propylamine

Guidance literature:: Multi-step reaction with 5 steps

1: 82 percent / t-BuOK / tetrahydrofuran / 2 h / Heating

2: 100 percent / H₂ / Pd/C / methanol / 2 h

3: NaOH / tetrahydrofuran / 16 h / 20 °C

4: 6.94 g / 4 h / 150 °C

5: 74 percent / LiAlH₄ / tetrahydrofuran / 16 h / Heating

With sodium hydroxide; lithium aluminium tetrahydride; potassium tert-butylate; hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol; 1: Horner-Emmons reaction / 2: Catalytic hydrogenation / 3: Hydrolysis / 4: Condensation / 5: Reduction;
DOI:10.1080/00397919908085886

Reference yield:

: 16980-82-8
3-(3-hydroxy-4-methoxyphenyl)-acrylic acid methyl ester

: 253135-13-6
N-benzyl-3-(3-hydroxy-4-methoxyphenyl)propylamine

Guidance literature:: Multi-step reaction with 4 steps

1: 100 percent / H₂ / Pd/C / methanol / 2 h

2: NaOH / tetrahydrofuran / 16 h / 20 °C

3: 6.94 g / 4 h / 150 °C

4: 74 percent / LiAlH₄ / tetrahydrofuran / 16 h / Heating

With sodium hydroxide; lithium aluminium tetrahydride; hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol; 1: Catalytic hydrogenation / 2: Hydrolysis / 3: Condensation / 4: Reduction;
DOI:10.1080/00397919908085886