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1,4-Diazaspiro[4.5]decan-2-one

Base Information
  • Chemical Name:1,4-Diazaspiro[4.5]decan-2-one
  • CAS No.:19718-88-8
  • Molecular Formula:C8H14N2O
  • Molecular Weight:154.212
  • Hs Code.:2933998090
  • DSSTox Substance ID:DTXSID30519837
  • Nikkaji Number:J2.812.443K
  • Wikidata:Q82383313
  • Mol file:19718-88-8.mol
1,4-Diazaspiro[4.5]decan-2-one

Synonyms:1,4-diazaspiro[4.5]decan-2-one;19718-88-8;1,4-diazaspiro[4.5]decan-3-one;SCHEMBL8029442;DTXSID30519837;FLZYHGIIDJMSJQ-UHFFFAOYSA-N;1,4-diazaspiro[4,5]decan-2-one;MFCD14584836;AKOS005071638;AE-0754;CS-0199355;E78017;J-503977

Suppliers and Price of 1,4-Diazaspiro[4.5]decan-2-one
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Matrix Scientific
  • 1,4-Diazaspiro[4.5]decan-2-one >95%
  • 500mg
  • $ 362.00
  • Crysdot
  • 1,4-Diazaspiro[4.5]decan-2-one 95+%
  • 1g
  • $ 427.00
  • Chemenu
  • 1,4-Diazaspiro[4.5]decan-2-one 95%
  • 1g
  • $ 403.00
  • American Custom Chemicals Corporation
  • 1,4-DIAZASPIRO[4.5]DECAN-2-ONE 95.00%
  • 500MG
  • $ 791.52
  • Ambeed
  • 1,4-Diazaspiro[4.5]decan-2-one 95+%
  • 250mg
  • $ 165.00
  • Ambeed
  • 1,4-Diazaspiro[4.5]decan-2-one 95+%
  • 100mg
  • $ 105.00
  • Ambeed
  • 1,4-Diazaspiro[4.5]decan-2-one 95+%
  • 1g
  • $ 435.00
  • Alichem
  • 1,4-Diazaspiro[4.5]decan-2-one
  • 1g
  • $ 448.24
  • AK Scientific
  • 1,4-Diazaspiro[4.5]decan-2-one
  • 500mg
  • $ 538.00
Total 9 raw suppliers
Chemical Property of 1,4-Diazaspiro[4.5]decan-2-one
Chemical Property:
  • PSA:41.13000 
  • LogP:1.02380 
  • XLogP3:0.6
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:2
  • Rotatable Bond Count:0
  • Exact Mass:154.110613074
  • Heavy Atom Count:11
  • Complexity:173
Purity/Quality:

98%min *data from raw suppliers

1,4-Diazaspiro[4.5]decan-2-one >95% *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:C1CCC2(CC1)NCC(=O)N2
  • General Description 1,4-Diazaspiro[4.5]decan-2-one is a spirocyclic compound that serves as a key intermediate in the synthesis of aminoquinoline derivatives via electrophilic rearrangement with Vilsmeier-Haack reagent, as well as in the environmentally friendly preparation of quinazolinones under mild, catalyst-free conditions. Its reactivity enables efficient transformations into structurally diverse heterocycles, including spiropiperidinequinazolinones, with high yields.
Technology Process of 1,4-Diazaspiro[4.5]decan-2-one

There total 5 articles about 1,4-Diazaspiro[4.5]decan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
at 20 ℃; for 72h; Neat (no solvent);
DOI:10.1002/ejoc.200901052
Guidance literature:
With triethylamine; In methanol; for 18h; Heating;
DOI:10.1080/00397910601033781
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