ETHYL 3-(2-OXO-2-PHENYLETHYL)BENZOATE

Base Information

• Chemical Name: ETHYL 3-(2-OXO-2-PHENYLETHYL)BENZOATE
• CAS No.: 898776-64-2
• Molecular Formula: C₁₇H₁₆O₃
• Molecular Weight: 268.312
• Hs Code.: 2918300090
• Mol file: 898776-64-2.mol

Synonyms:ETHYL 3-(2-OXO-2-PHENYLETHYL)BENZOATE;3-(2-Oxo-2-phenylethyl)benzoic Acid Ethyl Ester

Chemical Property of ETHYL 3-(2-OXO-2-PHENYLETHYL)BENZOATE

Chemical Property:

• Vapor Pressure: 5.05E-07mmHg at 25°C
• Boiling Point: 412.8°C at 760 mmHg
• Flash Point: 182.5°C
• PSA: 43.37000
• Density: 1.136g/cm³
• LogP: 3.28870

Purity/Quality:

97% ^*data from raw suppliers

3-(2-Oxo-2-phenylethyl)benzoicAcidEthylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A benzoic acid derivative.

Technology Process of ETHYL 3-(2-OXO-2-PHENYLETHYL)BENZOATE

There total 2 articles about ETHYL 3-(2-OXO-2-PHENYLETHYL)BENZOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

acetophenone (98-86-2) + ethyl 3-{[(4-methylphenyl)sulfonyl]oxy}benzoate (443296-77-3) → ethyl 3-(2-oxo-2-phenylethyl)benzoate (898776-64-2)

Guidance literature:

With potassium phosphate; 2-(2-(dicyclohexylphosphanyl)phenyl)-1,4,7-trimethyl-1H-indole; palladium diacetate; triethylamine; In tetrahydrofuran; tert-butyl alcohol; at 110 ℃; for 21h; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.orglett.6b00643

Reference yield: 61.0%

ethyl 3-((methylsulfonyl)oxy)benzoate (1070663-96-5) + acetophenone (98-86-2) → ethyl 3-(2-oxo-2-phenylethyl)benzoate (898776-64-2)

Guidance literature:

With potassium phosphate; 2-(2-(dicyclohexylphosphanyl)phenyl)-1,4,7-trimethyl-1H-indole; palladium diacetate; triethylamine; In tetrahydrofuran; tert-butyl alcohol; at 110 ℃; for 21h; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.orglett.6b00643

upstream raw materials:

acetophenone

ethyl 3-{[(4-methylphenyl)sulfonyl]oxy}benzoate

ethyl 3-((methylsulfonyl)oxy)benzoate