2-(6-Methylpyridin-3-yl)acetonitrile

Base Information

Chemical Name:2-(6-Methylpyridin-3-yl)acetonitrile
CAS No.:52426-67-2
Molecular Formula:C8H8N2
Molecular Weight:132.165
Hs Code.:2933399090
European Community (EC) Number:834-382-2
DSSTox Substance ID:DTXSID20466422
Wikidata:Q82292986
Mol file:52426-67-2.mol

Synonyms:2-(6-methylpyridin-3-yl)acetonitrile;52426-67-2;(6-Methyl-pyridin-3-yl)-acetonitrile;6-Methyl-3-pyridineacetonitrile;3-Pyridineacetonitrile, 6-methyl-;SCHEMBL1688808;DTXSID20466422;ZTPNSVPRINUIGX-UHFFFAOYSA-N;CCA42667;(6-methylpyridin-3-yl)-acetonitrile;MFCD09923952;AKOS016013838;SB37501;AS-36574;CS-0207777;EN300-41711

Suppliers and Price of 2-(6-Methylpyridin-3-yl)acetonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
6-Methyl-3-pyridineacetonitrile
50mg
$ 460.00

TRC
6-Methyl-3-pyridineacetonitrile
50mg
$ 165.00

Medical Isotopes, Inc.
6-Methyl-3-pyridineacetonitrile
500 mg
$ 2200.00

J&W Pharmlab
(6-Methyl-pyridin-3-yl)-acetonitrile 96%
500mg
$ 180.00

J&W Pharmlab
(6-Methyl-pyridin-3-yl)-acetonitrile 96%
1g
$ 260.00

J&W Pharmlab
(6-Methyl-pyridin-3-yl)-acetonitrile 96%
5g
$ 850.00

Crysdot
2-(6-Methylpyridin-3-yl)acetonitrile 95+%
1g
$ 353.00

American Custom Chemicals Corporation
2-(6-METHYLPYRIDIN-3-YL)ACETONITRILE 95.00%
2.5G
$ 1473.14

Alichem
2-Methylpyridine-5-acetonitrile
500mg
$ 1078.00

Alichem
2-Methylpyridine-5-acetonitrile
250mg
$ 741.20

Total 10 raw suppliers

Chemical Property of 2-(6-Methylpyridin-3-yl)acetonitrile

Chemical Property:

Vapor Pressure:0.014mmHg at 25°C
Boiling Point:257.871°C at 760 mmHg
Flash Point:99.053°C
PSA：36.68000
Density:1.056g/cm³
LogP:1.45608
Storage Temp.:2-8°C
XLogP3:0.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:132.068748264
Heavy Atom Count:10
Complexity:145

Purity/Quality:

97% ^*data from raw suppliers

6-Methyl-3-pyridineacetonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC=C(C=C1)CC#N
Uses 6-Methyl-3-pyridineacetonitrile is a reactant used in the preparation of pyrazolopyrimidine derivatives as agents for treatment of autoimmune diseases and orally active corticotropin-releasing factor receptor antagonists.

Technology Process of 2-(6-Methylpyridin-3-yl)acetonitrile

There total 5 articles about 2-(6-Methylpyridin-3-yl)acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 773837-37-9
sodium cyanide

: 52426-66-1
5-(chloromethyl)-2-methylpyridine

: 52426-67-2
2-(6-methylpyridin-3-yl)acetonitrile

Guidance literature:: In dimethyl sulfoxide; at 80 ℃; for 2h;

Reference yield: 80.0%

: 5-(2,2-difluorovinyl)-2-methylpyridine

: 52426-67-2
2-(6-methylpyridin-3-yl)acetonitrile

Guidance literature:: With ammonium hydroxide; In acetonitrile; at 60 ℃; for 24h; Sealed tube; Green chemistry;
DOI:10.1021/acs.orglett.1c04336