5-(Chloromethyl)-2-methylpyridine

Base Information

Chemical Name:5-(Chloromethyl)-2-methylpyridine
CAS No.:52426-66-1
Molecular Formula:C7H8ClN
Molecular Weight:141.6
Hs Code.:2933399090
DSSTox Substance ID:DTXSID80480765
Wikidata:Q82315825
Mol file:52426-66-1.mol

Synonyms:5-(CHLOROMETHYL)-2-METHYLPYRIDINE;52426-66-1;5-chloromethyl-2-methylpyridine;PYRIDINE, 5-(CHLOROMETHYL)-2-METHYL-;SCHEMBL395453;5-chlormethyl-2-methyl-pyridine;5-chloromethyl-2-methyl-pyridine;DTXSID80480765;ZDEBRYJZUMDNFA-UHFFFAOYSA-N;CCA42666;(6-methyl-3-pyridyl)methyl chloride;MFCD10697567;(6-methyl-3-pyridyl)-methyl chloride;AKOS009248661;AB59938;SY286776;D87733;EN300-104062;J-516317

Suppliers and Price of 5-(Chloromethyl)-2-methylpyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Chloromethyl-2-methylpyridine
1g
$ 1320.00

Labseeker
5-(CHLOROMETHYL)-2-METHYLPYRIDINE 95
25g
$ 1025.00

Crysdot
5-(Chloromethyl)-2-methylpyridine 95+%
1g
$ 377.00

Chemenu
5-(chloromethyl)-2-methylpyridine 95%
1g
$ 356.00

American Custom Chemicals Corporation
5-(CHLOROMETHYL)-2-METHYLPYRIDINE 95.00%
5MG
$ 502.90

Total 14 raw suppliers

Chemical Property of 5-(Chloromethyl)-2-methylpyridine

Chemical Property:

Vapor Pressure:0.204mmHg at 25°C
Refractive Index:1.527
Boiling Point:216.568 °C at 760 mmHg
PKA:5.18±0.10(Predicted)
Flash Point:105.279 °C
PSA：12.89000
Density:1.118 g/cm³
LogP:2.28490
Storage Temp.:2-8°C
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:141.0345270
Heavy Atom Count:9
Complexity:85

Purity/Quality:

97% ^*data from raw suppliers

5-Chloromethyl-2-methylpyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC=C(C=C1)CCl
Uses 5-Chloromethyl-2-methylpyridine is a reactant used in the preparation of substituted hydroxyadenine derivatives as potent interferon inducers.

Technology Process of 5-(Chloromethyl)-2-methylpyridine

There total 4 articles about 5-(Chloromethyl)-2-methylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 34107-46-5
6-methyl-3-pyridinemethanol

: 52426-66-1
5-(chloromethyl)-2-methylpyridine

Guidance literature:: With thionyl chloride; In dichloromethane; for 0.5h;

Reference yield: 89.0%

: 106651-81-4
3-(chloromethyl)-6-methylpyridine monohydrochloride

: 52426-66-1
5-(chloromethyl)-2-methylpyridine

Guidance literature:: With sodium hydroxide; In dichloromethane; water; pH=7 - 8;

Reference yield:

: 5470-70-2
Methyl 6-methylnicotinate

: 52426-66-1
5-(chloromethyl)-2-methylpyridine

Guidance literature:: Multi-step reaction with 2 steps

1: LiAlH₄ / tetrahydrofuran / 1 h / 20 °C

2: SOCl₂ / 4 h / 20 °C

With lithium aluminium tetrahydride; thionyl chloride; In tetrahydrofuran;
DOI:10.1021/jm040058e