1-ACETYL-PIPERIDINE-4-CARBOXYLIC ACID HYDRAZIDE

Base Information

• Chemical Name: 1-ACETYL-PIPERIDINE-4-CARBOXYLIC ACID HYDRAZIDE
• CAS No.: 69835-75-2
• Molecular Formula: C8H15N3O2
• Molecular Weight: 185.22
• Mol file: 69835-75-2.mol

Synonyms:1-ACETYL-PIPERIDINE-4-CARBOXYLIC ACID HYDRAZIDE;1-acetyl-4-carboxylhydrazide;1-Acetylpiperidine-4-carbohydrazide

Chemical Property of 1-ACETYL-PIPERIDINE-4-CARBOXYLIC ACID HYDRAZIDE

Chemical Property:

• Melting Point: 124-126 °C(Solv: ethyl acetate (141-78-6))
• Boiling Point: 441.8±34.0 °C(Predicted)
• PKA: 13.00±0.20(Predicted)
• PSA: 75.43000
• Density: 1.187±0.06 g/cm3(Predicted)
• LogP: 0.26390

Purity/Quality:

97% ^*data from raw suppliers

1-Acetyl-piperidine-4-carboxylicacidhydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-ACETYL-PIPERIDINE-4-CARBOXYLIC ACID HYDRAZIDE

There total 2 articles about 1-ACETYL-PIPERIDINE-4-CARBOXYLIC ACID HYDRAZIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-acetyl-piperidine-4-carboxylic acid methyl ester (126291-66-5) → 1-acetyl-piperidine-4-carboxylic acid hydrazide (69835-75-2)

Guidance literature:

With ethanol; hydrazine hydrate;

DOI:10.1021/ja01104a046

Reference yield:

isonipecotic acid methyl ester (2971-79-1) → 1-acetyl-piperidine-4-carboxylic acid hydrazide (69835-75-2)

Guidance literature:

Multi-step reaction with 2 steps

2: ethanol; N₂H₄+H₂O

With ethanol; hydrazine hydrate;

DOI:10.1021/ja01104a046

upstream raw materials:

1-acetyl-piperidine-4-carboxylic acid methyl ester

isonipecotic acid methyl ester