Ethanone, 1-(6-broMo-1H-pyrazolo[4,3-b]pyridin-1-yl)-

Base Information

Chemical Name:Ethanone, 1-(6-broMo-1H-pyrazolo[4,3-b]pyridin-1-yl)-
CAS No.:1383735-65-6
Molecular Formula:C8H6BrN3O
Molecular Weight:240.059
Hs Code.:
Mol file:1383735-65-6.mol

Synonyms:Ethanone, 1-(6-broMo-1H-pyrazolo[4,3-b]pyridin-1-yl)-;1-(6-bromo-1H-pyrazolo[4,3-b]pyridin-1-yl)ethanone

Suppliers and Price of Ethanone, 1-(6-broMo-1H-pyrazolo[4,3-b]pyridin-1-yl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(6-Bromo-1H-pyrazolo[4,3-b]pyridin-1-yl)ethanone 97%
1g
$ 842.00

Chemenu
1-(6-Bromo-1H-pyrazolo[4,3-b]pyridin-1-yl)ethanone 97%
1g
$ 795.00

Alichem
1-(6-Bromo-1H-pyrazolo[4,3-b]pyridin-1-yl)ethanone
1g
$ 697.68

Total 9 raw suppliers

Chemical Property of Ethanone, 1-(6-broMo-1H-pyrazolo[4,3-b]pyridin-1-yl)-

Chemical Property:

PSA：47.78000
LogP:1.85390

Purity/Quality:

99% ^*data from raw suppliers

1-(6-Bromo-1H-pyrazolo[4,3-b]pyridin-1-yl)ethanone 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Ethanone, 1-(6-broMo-1H-pyrazolo[4,3-b]pyridin-1-yl)-

There total 7 articles about Ethanone, 1-(6-broMo-1H-pyrazolo[4,3-b]pyridin-1-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 1301214-71-0
N-(5-bromo-2-methyl-pyridin-3-yl)-acetamide

: 1383735-65-6
1-{6-bromo-1H-pyrazolo[4,3-b]pyridin-1-yl}ethan-1-one

Guidance literature:: With 18-crown-6 ether; potassium carbonate; isopentyl nitrite; In chloroform; at 60 ℃; for 12h;
DOI:10.1016/j.bioorg.2022.105669

Reference yield: 48.0%

: 594-70-7
2-Methyl-2-nitropropane

: 1301214-71-0
N-(5-bromo-2-methyl-pyridin-3-yl)-acetamide

: 1383735-65-6
1-{6-bromo-1H-pyrazolo[4,3-b]pyridin-1-yl}ethan-1-one

Guidance literature:: N-(5-bromo-2-methyl-pyridin-3-yl)-acetamide; With potassium acetate; In toluene; at 80 ℃; for 0.5h; Inert atmosphere;

2-Methyl-2-nitropropane; With acetic anhydride; In toluene; at 80 ℃; for 18h;

Reference yield:

: 67443-38-3
5-bromo-2-chloro-3-nitropyridine

: 1383735-65-6
1-{6-bromo-1H-pyrazolo[4,3-b]pyridin-1-yl}ethan-1-one

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / -10 °C

1.2: 4 h

2.1: hydrogenchloride / water / 4 h / Reflux

3.1: acetic acid; iron / 2 h / Reflux

4.1: triethylamine / dichloromethane / 18 h

4.2: 1 h

5.1: acetic anhydride; potassium acetate; acetic acid; isopentyl nitrite / toluene / 3 h / Reflux

With hydrogenchloride; potassium acetate; acetic anhydride; iron; sodium hydride; acetic acid; triethylamine; isopentyl nitrite; In dichloromethane; water; N,N-dimethyl-formamide; toluene; mineral oil;