2-METHYL-4-(METHYLAMINO)BUTAN-2-OL

Base Information

• Chemical Name: 2-METHYL-4-(METHYLAMINO)BUTAN-2-OL
• CAS No.: 866223-53-2
• Molecular Formula: C6H15NO
• Molecular Weight: 117.19
• Hs Code.: 2922199090
• Mol file: 866223-53-2.mol

Synonyms:2-METHYL-4-(METHYLAMINO)BUTAN-2-OL;2-methyl-4-(methylamino)butan-2-ol(SALTDATA: FREE)

Chemical Property of 2-METHYL-4-(METHYLAMINO)BUTAN-2-OL

Chemical Property:

• Vapor Pressure: 0.296mmHg at 25°C
• Boiling Point: 178.5°C at 760 mmHg
• Flash Point: 60°C
• PSA: 32.26000
• Density: 0.874g/cm³
• LogP: 0.75770

Purity/Quality:

97% ^*data from raw suppliers

2-?Methyl-?4-?(methylamino)?butan-?2-?ol ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22-41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-METHYL-4-(METHYLAMINO)BUTAN-2-OL

There total 1 articles about 2-METHYL-4-(METHYLAMINO)BUTAN-2-OL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.3%

methylmagnesium bromide (75-16-1) + methyl-3-(N-methyl-N-trifluoroacetyl)aminopropionate (844439-50-5) → 4-(N-methylamino)-2-methyl-2-butanol (866223-53-2)

Guidance literature:

In diethyl ether; for 1.5h; Inert atmosphere; Reflux;

DOI:10.1021/jo301919e

Reference yield: 80.0%

4-(N-methylamino)-2-methyl-2-butanol (866223-53-2) + phenylpropyolic acid (637-44-5) → N-(3-hydroxy-3-methylbutyl)-N-methyl-3-phenylpropiolamide

Guidance literature:

phenylpropyolic acid; With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In acetonitrile; at 20 ℃; for 0.5h;

4-(N-methylamino)-2-methyl-2-butanol; With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 0 ℃; for 3h;

DOI:10.1021/ol503273v

Reference yield:

4-(N-methylamino)-2-methyl-2-butanol (866223-53-2) + phenylpropyolic acid (637-44-5) → (Z)-2,2,5-trimethyl-8-phenyl-4,5-dihydro-2H-1,5-oxazocen-6(3H)-one

Guidance literature:

Multi-step reaction with 2 steps

1.1: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / acetonitrile / 0.5 h / 20 °C

1.2: 3 h / 0 °C

2.1: silver trifluoromethanesulfonate; C₁₈F₁₅P*Ag⁽¹⁺⁾*Cl^(1-) / dichloromethane / 48 h / 20 °C

With C₁₈F₁₅P*Ag⁽¹⁺⁾*Cl^(1-); silver trifluoromethanesulfonate; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In dichloromethane; acetonitrile;

DOI:10.1021/ol503273v

upstream raw materials:

methylmagnesium bromide

methyl-3-(N-methyl-N-trifluoroacetyl)aminopropionate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 866223-53-2 2-METHYL-4-(METHYLAMINO)BUTAN-2-OL

Send

Send

Metric Ton KG G Pound L ML

Send

Send