(2S,3S,4R)-2-Azido-3,4-bis[(tert-butyldimethylsilyl)oxy]-1-octadecanol

Base Information

Chemical Name:(2S,3S,4R)-2-Azido-3,4-bis[(tert-butyldimethylsilyl)oxy]-1-octadecanol
CAS No.:1256376-21-2
Molecular Formula:C30H65N3O3Si2
Molecular Weight:572.035
Hs Code.:
Mol file:1256376-21-2.mol

Synonyms:(2S,3S,4R)-2-Azido-3,4-bis[(tert-butyldimethylsilyl)oxy]-1-octadecanol;(2S,3S,4R)-2-Azido-3,4-bis(tert-butyldiMethylsilyl)-1,3,4-octadecanetriol;(2S,3S,4R)-2-Azido-3,4-bis[[(1,1-diMethylethyl)diMethylsilyl]oxy]-1-octadecanol

Suppliers and Price of (2S,3S,4R)-2-Azido-3,4-bis[(tert-butyldimethylsilyl)oxy]-1-octadecanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2S,3S,4R)-2-Azido-3,4-bis[(tert-butyldimethylsilyl)oxy]-1-octadecanol
25mg
$ 1320.00

Total 2 raw suppliers

Chemical Property of (2S,3S,4R)-2-Azido-3,4-bis[(tert-butyldimethylsilyl)oxy]-1-octadecanol

Chemical Property:

PSA：88.44000
LogP:9.98236
Solubility.:Dichloromethane, Ethyl Acetate, Methanol

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

(2S,3S,4R)-2-Azido-3,4-bis[(tert-butyldimethylsilyl)oxy]-1-octadecanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (2S,3S,4R)-2-Azido-3,4-bis[(tert-butyldimethylsilyl)oxy]-1-octadecanol

There total 2 articles about (2S,3S,4R)-2-Azido-3,4-bis[(tert-butyldimethylsilyl)oxy]-1-octadecanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1256376-20-1
(2S,3S,4R)-2-azido-1,3,4-tri-tert-butyldimethylsilyloxy-1,3,4-octadecanetriol

: 1256376-21-2
(2S,3S,4R)-2-azido-3,4-bis-tert-butyldimethylsilyloxy-1-octadecaneol

Guidance literature:: With trifluoroacetic acid; In tetrahydrofuran; water; at 0 ℃; Inert atmosphere;
DOI:10.1016/j.tet.2013.06.051

Reference yield:

: 201002-41-7
(2R,3S,4R)-2-azidooctadecane-1,3,4-triol

: 1256376-21-2
(2S,3S,4R)-2-azido-3,4-bis-tert-butyldimethylsilyloxy-1-octadecaneol

Guidance literature:: Multi-step reaction with 2 steps

1: 2,6-dimethylpyridine / dichloromethane / 2.5 h / 0 - 20 °C / Inert atmosphere

2: trifluoroacetic acid / water; tetrahydrofuran / 0 °C / Inert atmosphere

With 2,6-dimethylpyridine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; water;
DOI:10.1016/j.tet.2013.06.051

Reference yield: 65.0%

: 1256376-21-2
(2S,3S,4R)-2-azido-3,4-bis-tert-butyldimethylsilyloxy-1-octadecaneol

: 90358-01-3
2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl trichloroacetimidate

: 1256376-22-3
(2S,3S,4R)-1-O-(2',3',4',6'-tetra-O-benzyl-α-D-galactopyranosyl)-2-azido-3,4-di-tert-butyldimethylsilyloxyoctadecane

Guidance literature:: With boron trifluoride diethyl etherate; In tetrahydrofuran; diethyl ether; at -20 ℃; for 18h; stereoselective reaction; Molecular sieve; Inert atmosphere;
DOI:10.1055/s-0029-1218844