(2S,3S,4R)-1-O-(2',3',4',6'-tetra-O-benzyl-α-D-galactopyranosyl)-2-azido-3,4-di-tert-butyldimethylsilyloxyoctadecane

Base Information

Chemical Name:(2S,3S,4R)-1-O-(2',3',4',6'-tetra-O-benzyl-α-D-galactopyranosyl)-2-azido-3,4-di-tert-butyldimethylsilyloxyoctadecane
CAS No.:1256376-22-3
Molecular Formula:C₆₄H₉₉N₃O₈Si₂
Molecular Weight:1094.68
Hs Code.:

Synonyms:(2S,3S,4R)-1-O-(2',3',4',6'-tetra-O-benzyl-α-D-galactopyranosyl)-2-azido-3,4-di-tert-butyldimethylsilyloxyoctadecane

Suppliers and Price of (2S,3S,4R)-1-O-(2',3',4',6'-tetra-O-benzyl-α-D-galactopyranosyl)-2-azido-3,4-di-tert-butyldimethylsilyloxyoctadecane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3S,4R)-1-O-(2',3',4',6'-tetra-O-benzyl-α-D-galactopyranosyl)-2-azido-3,4-di-tert-butyldimethylsilyloxyoctadecane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3S,4R)-1-O-(2',3',4',6'-tetra-O-benzyl-α-D-galactopyranosyl)-2-azido-3,4-di-tert-butyldimethylsilyloxyoctadecane

There total 4 articles about (2S,3S,4R)-1-O-(2',3',4',6'-tetra-O-benzyl-α-D-galactopyranosyl)-2-azido-3,4-di-tert-butyldimethylsilyloxyoctadecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 1256376-21-2
(2S,3S,4R)-2-azido-3,4-bis-tert-butyldimethylsilyloxy-1-octadecaneol

: 90358-01-3
2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl trichloroacetimidate

: 1256376-22-3
(2S,3S,4R)-1-O-(2',3',4',6'-tetra-O-benzyl-α-D-galactopyranosyl)-2-azido-3,4-di-tert-butyldimethylsilyloxyoctadecane

Guidance literature:: With boron trifluoride diethyl etherate; In tetrahydrofuran; diethyl ether; at -20 ℃; for 18h; stereoselective reaction; Molecular sieve; Inert atmosphere;
DOI:10.1055/s-0029-1218844

Reference yield: 53.0%

: 1256376-21-2
(2S,3S,4R)-2-azido-3,4-bis-tert-butyldimethylsilyloxy-1-octadecaneol

: 211678-08-9
p-methylphenyl 2,3,4,6-tetra-O-benzyl-1-thio-β-D-galactopyranoside

: 1256376-22-3
(2S,3S,4R)-1-O-(2',3',4',6'-tetra-O-benzyl-α-D-galactopyranosyl)-2-azido-3,4-di-tert-butyldimethylsilyloxyoctadecane

: 1448529-89-2
(2S,3S,4R)-1-O-(2',3',4',6'-tetra-O-benzyl-β-D-galactopyranosyl)-2-azido-3,4-di-tert-butyldimethylsilyloxyoctadecane

Guidance literature:: With N-iodo-succinimide; trifluorormethanesulfonic acid; In diethyl ether; dichloromethane; at 20 ℃; for 2h; Inert atmosphere; Molecular sieve;
DOI:10.1016/j.tet.2013.06.051

Reference yield:

: 201002-41-7
(2R,3S,4R)-2-azidooctadecane-1,3,4-triol

: 1256376-22-3
(2S,3S,4R)-1-O-(2',3',4',6'-tetra-O-benzyl-α-D-galactopyranosyl)-2-azido-3,4-di-tert-butyldimethylsilyloxyoctadecane

Guidance literature:: Multi-step reaction with 3 steps

1: 2,6-dimethylpyridine / dichloromethane / 2.5 h / 0 - 20 °C / Inert atmosphere

2: trifluoroacetic acid / water; tetrahydrofuran / 0 °C / Inert atmosphere

3: N-iodo-succinimide; trifluorormethanesulfonic acid / dichloromethane; diethyl ether / 2 h / 20 °C / Inert atmosphere; Molecular sieve

With 2,6-dimethylpyridine; N-iodo-succinimide; trifluorormethanesulfonic acid; trifluoroacetic acid; In tetrahydrofuran; diethyl ether; dichloromethane; water;
DOI:10.1016/j.tet.2013.06.051