2-Cyano-3-(4-hydroxyphenyl)prop-2-enoic acid

Base Information

Chemical Name:2-Cyano-3-(4-hydroxyphenyl)prop-2-enoic acid
CAS No.:28166-41-8
Molecular Formula:C₁₀H₇NO₃
Molecular Weight:189.17
Hs Code.:29269090
European Community (EC) Number:248-879-1
NSC Number:173138
ChEMBL ID:CHEMBL3965817
Mol file:28166-41-8.mol

Synonyms:CHEMBL3965817;2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid;NSC-173138;2-Cyano-3-(4-hydroxyphenyl)acrylic acid;CHC;ACCA;|A-CHCA;SCHEMBL437568;|A-cyano-4-hydroxy-cinnamic acid;BDBM50198890;NSC173138;?-CYANO-4-HYDROXYCINNAMIC ACID;2-cyano-3-(4-hydroxyphe-nyl)acrylic acid;EN300-100956;Z44303375

Suppliers and Price of 2-Cyano-3-(4-hydroxyphenyl)prop-2-enoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
α-Cyano-4-hydroxycinnamic acid
2.5g
$ 85.00

TCI Chemical
alpha-Cyano-4-hydroxycinnamic Acid >98.0%(HPLC)(T)
1g
$ 95.00

Sigma-Aldrich
α-Cyano-4-hydroxycinnamic acid 97%
5g
$ 46.20

Sigma-Aldrich
α-Cyano-4-hydroxycinnamic acid matrixsubstanceforMALDI-MS,≥99.0%(HPLC)
250 mg
$ 32.40

Sigma-Aldrich
α-Cyano-4-hydroxycinnamic acid 99%
2g
$ 31.40

Sigma-Aldrich
α-Cyano-4-hydroxycinnamic acid matrix substance for MALDI-MS, ≥99.0% (HPLC)
250mg-f
$ 31.40

Sigma-Aldrich
α-Cyano-4-hydroxycinnamic acid 99%
10g
$ 62.50

Sigma-Aldrich
α-Cyano-4-hydroxycinnamic acid ≥98% (TLC), powder
10g
$ 62.50

Sigma-Aldrich
α-Cyano-4-hydroxycinnamic acid ≥98% (TLC), powder
25g
$ 131.00

Sigma-Aldrich
α-Cyano-4-hydroxycinnamic acid 97%
25g
$ 131.00

Total 33 raw suppliers

Chemical Property of 2-Cyano-3-(4-hydroxyphenyl)prop-2-enoic acid

Chemical Property:

Appearance/Colour:yellow crystalline powder
Vapor Pressure:4.73E-07mmHg at 25°C
Melting Point:245-250 °C(lit.)
Refractive Index:1.5400 (estimate)
Boiling Point:398.1 °C at 760 mmHg
PKA:0.85±0.10(Predicted)
Flash Point:194.5 °C
PSA：81.32000
Density:1.42g/cm³
LogP:1.38378
Storage Temp.:2-8°C
Solubility.:methanol: 10 mg/mL, clear
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:189.042593085
Heavy Atom Count:14
Complexity:292

Purity/Quality:

98%,99%, ^*data from raw suppliers

α-Cyano-4-hydroxycinnamic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC(=CC=C1C=C(C#N)C(=O)O)O
Isomeric SMILES:C1=CC(=CC=C1/C=C(/C#N)\C(=O)O)O
Recent ClinicalTrials:Buprenorphine for Prisoners
Uses inhibitor of mitochondrial pyruvate transport α-Cyano-4-hydroxycinnamic acid (CHC) was used in encapsulation of CHC into NaY zeolite. It was used as matrix to investigate the activity of the paclitaxel derivatives using several well-established in vitro angiogenesis assays. α-Cyano-4-hydroxycinnamic acid(CHC) was used as a matrix for peptides and nucleotides in mass spectroscopic analysis. It was used in encapsulation of CHC into NaY zeolite. It was used as matrix to investigate the activity of the paclitaxel derivatives using several well-established in vitro angiogenesis assays.

Technology Process of 2-Cyano-3-(4-hydroxyphenyl)prop-2-enoic acid

There total 9 articles about 2-Cyano-3-(4-hydroxyphenyl)prop-2-enoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%