methyl 2-[(2,6-dichlorobenzyl)amino]-3-(4-nitrophenyl)propanoate

Base Information

• Chemical Name: methyl 2-[(2,6-dichlorobenzyl)amino]-3-(4-nitrophenyl)propanoate
• CAS No.: 623146-90-7
• Molecular Formula: C₁₇H₁₆Cl₂N₂O₄
• Molecular Weight: 383.231
• Mol file: 623146-90-7.mol

Synonyms:methyl 2-[(2,6-dichlorobenzyl)amino]-3-(4-nitrophenyl)propanoate

Chemical Property of methyl 2-[(2,6-dichlorobenzyl)amino]-3-(4-nitrophenyl)propanoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of methyl 2-[(2,6-dichlorobenzyl)amino]-3-(4-nitrophenyl)propanoate

There total 1 articles about methyl 2-[(2,6-dichlorobenzyl)amino]-3-(4-nitrophenyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

methyl 2-amino-3-(4-nitrophenyl)propionate (85317-52-8) + 2,6-Dichlorobenzyl bromide (20443-98-5) → methyl 2-[(2,6-dichlorobenzyl)amino]-3-(4-nitrophenyl)propanoate (623146-90-7)

Guidance literature:

With potassium carbonate; In acetonitrile; at 20 ℃; for 6h;

Reference yield: 62.0%

methyl 2-[(2,6-dichlorobenzyl)amino]-3-(4-nitrophenyl)propanoate (623146-90-7) → methyl 3-(4-aminophenyl)-2-[(2,6-dichlorobenzyl)amino]propanoate (623146-91-8)

Guidance literature:

With hydrogen; platinum(IV) oxide; In acetic acid; at 20 ℃; for 0.25 - 0.333333h; under 517.162 - 775.743 Torr;

upstream raw materials:

methyl 2-amino-3-(4-nitrophenyl)propionate

2,6-Dichlorobenzyl bromide

Downstream raw materials:

methyl 3-(4-aminophenyl)-2-[(2,6-dichlorobenzyl)amino]propanoate