3-[Nitroso(benzyloxy)amino]-N-[(benzyloxy)carbonyl]-D,L-alanine

Base Information

Chemical Name:3-[Nitroso(benzyloxy)amino]-N-[(benzyloxy)carbonyl]-D,L-alanine
CAS No.:1286490-16-1
Molecular Formula:C₁₈H₁₉N₃O₆
Molecular Weight:373.365
Hs Code.:
Mol file:1286490-16-1.mol

Synonyms:3-[Nitroso(benzyloxy)amino]-N-[(benzyloxy)carbonyl]-D,L-alanine

Suppliers and Price of 3-[Nitroso(benzyloxy)amino]-N-[(benzyloxy)carbonyl]-D,L-alanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-[Nitroso(benzyloxy)amino]-N-[(benzyloxy)carbonyl]-D,L-alanine
500mg
$ 1230.00

Medical Isotopes, Inc.
3-[Nitroso(benzyloxy)amino]-N-[(benzyloxy)carbonyl]-D,L-alanine
50 mg
$ 640.00

Total 2 raw suppliers

Chemical Property of 3-[Nitroso(benzyloxy)amino]-N-[(benzyloxy)carbonyl]-D,L-alanine

Chemical Property:

PSA：121.02000
LogP:2.68560
Solubility.:Dichloromethane, Ethyl Acetate

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

3-[Nitroso(benzyloxy)amino]-N-[(benzyloxy)carbonyl]-D,L-alanine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Intermediate for synthesis of D,L-Alanosine.

Technology Process of 3-[Nitroso(benzyloxy)amino]-N-[(benzyloxy)carbonyl]-D,L-alanine

There total 5 articles about 3-[Nitroso(benzyloxy)amino]-N-[(benzyloxy)carbonyl]-D,L-alanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 337368-14-6,96521-76-5
(S)-3-[(phenylmethyloxy)amino]-N-[(phenylmethyloxy)carbonyl]alanine

: 832090-73-0,1286490-16-1
(S)-3-[nitroso(phenylmethyloxy)amino]-N-[(phenylmethyloxy)carbonyl]alanine

Guidance literature:: With n-Butyl nitrite; In dichloromethane; at 20 ℃; for 1h;
DOI:10.1002/ejoc.200400508

Reference yield:

: 1145-80-8
N-(benzyloxycarbonyl)-L-serine

: 832090-73-0,1286490-16-1
(S)-3-[nitroso(phenylmethyloxy)amino]-N-[(phenylmethyloxy)carbonyl]alanine

Guidance literature:: Multi-step reaction with 4 steps

1: 80 percent / DCC / acetonitrile / 0 - 20 °C

2: 87 percent / PPh₃; Et₃N / acetonitrile; CCl₄ / 24 h / 20 °C

3: 99 percent / LiOH*H₂O / tetrahydrofuran; H₂O / 20 °C

4: 99 percent / nBuONO / CH₂Cl₂ / 1 h / 20 °C

With lithium hydroxide; n-Butyl nitrite; triethylamine; dicyclohexyl-carbodiimide; triphenylphosphine; In tetrahydrofuran; tetrachloromethane; dichloromethane; water; acetonitrile;
DOI:10.1002/ejoc.200400508

Reference yield:

: 622-33-3
N-benzyloxyamine

: 832090-73-0,1286490-16-1
(S)-3-[nitroso(phenylmethyloxy)amino]-N-[(phenylmethyloxy)carbonyl]alanine

Guidance literature:: Multi-step reaction with 4 steps

1: 80 percent / DCC / acetonitrile / 0 - 20 °C

2: 87 percent / PPh₃; Et₃N / acetonitrile; CCl₄ / 24 h / 20 °C

3: 99 percent / LiOH*H₂O / tetrahydrofuran; H₂O / 20 °C

4: 99 percent / nBuONO / CH₂Cl₂ / 1 h / 20 °C

With lithium hydroxide; n-Butyl nitrite; triethylamine; dicyclohexyl-carbodiimide; triphenylphosphine; In tetrahydrofuran; tetrachloromethane; dichloromethane; water; acetonitrile;
DOI:10.1002/ejoc.200400508