2-Hydroxyquinoline-6-sulfonyl chloride

Base Information

Chemical Name:2-Hydroxyquinoline-6-sulfonyl chloride
CAS No.:569340-07-4
Molecular Formula:C9H6ClNO3S
Molecular Weight:243.671
Hs Code.:
European Community (EC) Number:818-682-0
DSSTox Substance ID:DTXSID50696851
Wikidata:Q82626572
Mol file:569340-07-4.mol

Synonyms:2-Hydroxyquinoline-6-sulfonyl chloride;569340-07-4;2-OXO-1,2-DIHYDROQUINOLINE-6-SULFONYL CHLORIDE;2-oxo-1H-quinoline-6-sulfonyl chloride;SCHEMBL3223011;DTXSID50696851;YEYHIOACCQXLCJ-UHFFFAOYSA-N;MFCD18300284;AKOS012545290;AKOS023378425;SY042538;CS-0080680;EN300-84909;2-oxidanylidene-1H-quinoline-6-sulfonyl chloride;2-Oxo-1 ,2-dihydro-quinoline-6-sulfonyl chloride;2-Oxo-1,2-dihydro-quinoline-6-sulfonyl chloride;A831239

Suppliers and Price of 2-Hydroxyquinoline-6-sulfonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Hydroxyquinoline-6-sulfonylchloride 95+%
1g
$ 424.00

American Custom Chemicals Corporation
2-HYDROXYQUINOLINE-6-SULFONYL CHLORIDE 95.00%
5MG
$ 505.05

Alichem
2-Hydroxyquinoline-6-sulfonylchloride
1g
$ 419.44

AK Scientific
2-Hydroxyquinoline-6-sulfonylchloride
1g
$ 667.00

Total 13 raw suppliers

Chemical Property of 2-Hydroxyquinoline-6-sulfonyl chloride

Chemical Property:

Boiling Point:473.5±45.0 °C(Predicted)
PKA:10.15±0.70(Predicted)
PSA：75.38000
Density:1.535±0.06 g/cm3(Predicted)
LogP:2.53640
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:242.9756919
Heavy Atom Count:15
Complexity:398

Purity/Quality:

≥95% ^*data from raw suppliers

2-Hydroxyquinoline-6-sulfonylchloride 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=CC(=O)N2)C=C1S(=O)(=O)Cl
Uses 2-?oxo-?1,?2-?Dhydroquinoline-?6-?sulfonyl chloride is a reagent used in organic synthesis of pharmaceuticals.

Technology Process of 2-Hydroxyquinoline-6-sulfonyl chloride

There total 3 articles about 2-Hydroxyquinoline-6-sulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 59-31-4,70254-42-1,493-62-9
2-quinolone

: 569340-07-4
2-oxo-1,2-dihydro-6-quinolinesulfonyl chloride

Guidance literature:: With chlorosulfonic acid; at 90 ℃; for 3h;

Reference yield: 68.0%

: 7790-94-5
chlorosulfonic acid

: 59-31-4
2-hydroxyquinoline

: 569340-07-4
2-oxo-1,2-dihydro-6-quinolinesulfonyl chloride

Guidance literature:: at 65 ℃; for 3h; Inert atmosphere;
DOI:10.1016/j.bmc.2014.05.001

Reference yield: 4.0%

: 79207-68-4
6-amino-2(1H)-quinolinone

: 569340-07-4
2-oxo-1,2-dihydro-6-quinolinesulfonyl chloride

Guidance literature:: 6-amino-2(1H)-quinolinone; With hydrogenchloride; sodium nitrite; In water; acetic acid; acetonitrile; at -5 - 0 ℃; for 0.5h;

With sulfur dioxide; In water; acetic acid; acetonitrile; at -5 - 0 ℃; for 2h;

With sulfur dioxide; copper dichloride; In water; acetic acid; acetonitrile; at -5 - 20 ℃;