(S)-2-HYDROXY-3-(4-METHOXY-PHENYL)-PROPIONIC ACID ETHYL ESTER

Base Information

• Chemical Name: (S)-2-HYDROXY-3-(4-METHOXY-PHENYL)-PROPIONIC ACID ETHYL ESTER
• CAS No.: 38618-53-0
• Molecular Formula: C12H16O4
• Molecular Weight: 224.25
• Hs Code.: 2918990090
• Mol file: 38618-53-0.mol

Synonyms:2S-HYDROXY-3-(4-METHOXY-PHENYL)-PROPIONIC ACID ETHYL ESTER;(S)-2-HYDROXY-3-(4-METHOXY-PHENYL)-PROPIONIC ACID ETHYL ESTER;Benzenepropanoic acid, a-hydroxy-4-Methoxy-, ethyl ester;ethyl 2-hydroxy-3-(4-Methoxyphenyl)propanoate;Benzenepropanoic acid, .alpha.-hydroxy-4-methoxy-, ethyl ester

Chemical Property of (S)-2-HYDROXY-3-(4-METHOXY-PHENYL)-PROPIONIC ACID ETHYL ESTER

Chemical Property:

• Vapor Pressure: 2.57E-05mmHg at 25°C
• Boiling Point: 344.1°C at 760 mmHg
• Flash Point: 128°C
• PSA: 55.76000
• Density: 1.137g/cm³
• LogP: 1.16170

Purity/Quality:

97% ^*data from raw suppliers

2-Hydroxy-3-(4-methoxy-phenyl)-propionicacidethylester 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-2-HYDROXY-3-(4-METHOXY-PHENYL)-PROPIONIC ACID ETHYL ESTER

There total 2 articles about (S)-2-HYDROXY-3-(4-METHOXY-PHENYL)-PROPIONIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 3-(4-methoxyphenyl)-2,3-epoxypropionate (16546-01-3) → ethyl 2-hydroxy-3-(4-methoxyphenyl)propanoate (38618-53-0)

Guidance literature:

With 5%-palladium/activated carbon; hydrogen; In ethanol; for 72h; under 3620.13 Torr;

DOI:10.1016/j.tetasy.2009.10.013

Reference yield:

ethanol (64-17-5) + 2-Hydroxy-3-(4-methoxy-phenyl)-propionitrile → ethyl 2-hydroxy-3-(4-methoxyphenyl)propanoate (38618-53-0)

Guidance literature:

With hydrogenchloride;

Reference yield: 98.0%

ethyl 2-hydroxy-3-(4-methoxyphenyl)propanoate (38618-53-0) + acetic anhydride (108-24-7) → ethyl 2-acetoxy-3-(4-methoxyphenyl)propanoate (125986-63-2)

Guidance literature:

With pyridine; In dichloromethane; Cooling with ice;

DOI:10.1016/j.tetasy.2009.10.013

upstream raw materials:

ethanol

ethyl 3-(4-methoxyphenyl)-2,3-epoxypropionate

Downstream raw materials:

ethyl 2-ethoxy-3-(4-methoxyphenyl)propanoate

ethyl (R)-2-hydroxy-3-(4-methoxyphenyl)propanoate

ethyl (S)-2-acetoxy-3-(4-methoxyphenyl)propanoate

(R)-2-hydroxy-3-(4-methoxyphenyl)propanoic acid