MONODESETHYL QUINACRINE, DIHYDROCHLORIDE

Base Information

• Chemical Name: MONODESETHYL QUINACRINE, DIHYDROCHLORIDE
• CAS No.: 908844-46-2
• Molecular Formula: C21H28Cl3N3O
• Molecular Weight: 444.83
• Mol file: 908844-46-2.mol

Synonyms:MONODESETHYL QUINACRINE, DIHYDROCHLORIDE;N4-(6-Chloro-2-Methoxy-9-acridinyl)-N1-ethyl-1,4-pentanediaMine

Chemical Property of MONODESETHYL QUINACRINE, DIHYDROCHLORIDE

Chemical Property:

• Melting Point: >200°C
• PSA: 49.41000
• LogP: 5.05290
• Storage Temp.: -20°C Freezer
• Solubility.: Methanol (Slightly, Heated)

Purity/Quality:

97% ^*data from raw suppliers

Monodesethyl quinacrine, dihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A metabolite of Quinacrine, an antimalarial compound A metabolite of Quinacrine, an antimalarial compound.

Technology Process of MONODESETHYL QUINACRINE, DIHYDROCHLORIDE

There total 3 articles about MONODESETHYL QUINACRINE, DIHYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

quinacrine dihydrochloride (69-05-6) → Mono-desethyl quinacrine (908844-46-2) + 6-chloro-2-methoxyacridone (13161-87-0) + N4,N4-diethyl-N1-(6-chloro-2-methoxy-acridin-9-yl)-1-methyl-butanediyldiamine-N4-oxide (83196-72-9)

Guidance literature:

With dihydrogen peroxide; In water; at 25 ℃; for 24h;

DOI:10.1002/jps.22543

Reference yield:

quinacrine dihydrochloride (69-05-6) → 2-methoxy-6-chloro-acridine (21332-86-5) + Mono-desethyl quinacrine (908844-46-2) + 6-chloro-2-methoxyacridone (13161-87-0) + 6-chloro-9-[(4-diethylamino-1-methyl-butyl)amino]acridin-2-ol (854892-24-3) + N4,N4-diethyl-N1-(6-chloro-2-methoxy-acridin-9-yl)-1-methyl-butanediyldiamine-N4-oxide (83196-72-9)

Guidance literature:

With water; Photolysis;

DOI:10.1002/jps.22543

Reference yield:

quinacrine dihydrochloride (69-05-6) → Mono-desethyl quinacrine (908844-46-2)

Guidance literature:

at 250 ℃;

DOI:10.1002/jps.22543

upstream raw materials:

quinacrine dihydrochloride