6-Chloro-2-methoxyacridine

Base Information

• Chemical Name: 6-Chloro-2-methoxyacridine
• CAS No.: 21332-86-5
• Molecular Formula: C14H10ClNO
• DSSTox Substance ID: DTXSID60598291
• Wikidata: Q82494034
• Mol file: 21332-86-5.mol

Synonyms:6-chloro-2-methoxyacridine;21332-86-5;SCHEMBL278565;DTXSID60598291

Chemical Property of 6-Chloro-2-methoxyacridine

Chemical Property:

• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 243.0450916
• Heavy Atom Count: 17
• Complexity: 273

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC2=C(C=C1)N=C3C=C(C=CC3=C2)Cl

Technology Process of 6-Chloro-2-methoxyacridine

There total 2 articles about 6-Chloro-2-methoxyacridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

quinacrine dihydrochloride (69-05-6) → 2-methoxy-6-chloro-acridine (21332-86-5) + Mono-desethyl quinacrine (908844-46-2) + 6-chloro-2-methoxyacridone (13161-87-0) + 6-chloro-9-[(4-diethylamino-1-methyl-butyl)amino]acridin-2-ol (854892-24-3) + N4,N4-diethyl-N1-(6-chloro-2-methoxy-acridin-9-yl)-1-methyl-butanediyldiamine-N4-oxide (83196-72-9)

Guidance literature:

With water; Photolysis;

DOI:10.1002/jps.22543

Reference yield:

quinacrine dihydrochloride (69-05-6) → 2-methoxy-6-chloro-acridine (21332-86-5) + 6-chloro-2-methoxyacridin-9-amine (3548-09-2)

Guidance literature:

With oxygen; In water; at 25 ℃; Quantum yield; Mechanism; Irradiation; influence of pH and partial O₂ pressure, further reagent: methylene blue, benzoylperoxide;

DOI:10.1515/znb-1984-1128

upstream raw materials:

quinacrine dihydrochloride