1-ISOPROPYL-1H-INDOLE-6-CARBALDEHYDE

Base Information

• Chemical Name: 1-ISOPROPYL-1H-INDOLE-6-CARBALDEHYDE
• CAS No.: 921602-58-6
• Molecular Formula: C12H13NO
• Molecular Weight: 187.241
• Mol file: 921602-58-6.mol

Synonyms:1-ISOPROPYL-1H-INDOLE-6-CARBALDEHYDE;1H-indole-6-carboxaldehyde, 1-(1-methylethyl)-

Chemical Property of 1-ISOPROPYL-1H-INDOLE-6-CARBALDEHYDE

Chemical Property:

• PSA: 22.00000
• LogP: 3.03470

Purity/Quality:

97% ^*data from raw suppliers

1-Isopropyl-1H-indole-6-carbaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-ISOPROPYL-1H-INDOLE-6-CARBALDEHYDE

There total 1 articles about 1-ISOPROPYL-1H-INDOLE-6-CARBALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

2-iodo-propane (75-30-9) + indole-6-carboxaldehyde (1196-70-9) → 1-isopropyl-1H-indole-6-carbaldehyde (921602-58-6)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 0 - 50 ℃; for 8h;

Reference yield: 53.0%

3-(4-aminophenyl)propionic acid (2393-17-1) + 1-isopropyl-1H-indole-6-carbaldehyde (921602-58-6) → 3-{4-[(1-isopropyl-1H-indol-6-ylmethyl)amino]phenyl}propanoic acid (1609964-45-5)

Guidance literature:

With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 20 ℃; for 8h;

Reference yield:

1-isopropyl-1H-indole-6-carbaldehyde (921602-58-6) + C21H23N3O4*C2HF3O2 → (6S)-6-benzyl-4-[(5-methoxy-1H-indol-2-yl)carbonyl]-1-{[1-(propan-2-yl)-1H-indol-6-yl]methyl}piperazin-2-one

Guidance literature:

1-isopropyl-1H-indole-6-carbaldehyde; C₂₁H₂₃N₃O₄*C₂HF₃O₂; With sodium tris(acetoxy)borohydride; triethylamine; In 1,2-dichloro-ethane; at 20 ℃; for 18h;

With sodium hydrogencarbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 8h;

DOI:10.1016/j.bmcl.2019.08.024

upstream raw materials:

2-iodo-propane

indole-6-carboxaldehyde

Downstream raw materials:

3-{4-[(1-isopropyl-1H-indol-6-ylmethyl)amino]phenyl}propanoic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 921602-58-6 1-ISOPROPYL-1H-INDOLE-6-CARBALDEHYDE

Send

Send

Metric Ton KG G Pound L ML

Send

Send