((2R,3R)-3-[2-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-ETHYL]-OXIRANYL)-METHANOL

Base Information

Chemical Name:((2R,3R)-3-[2-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-ETHYL]-OXIRANYL)-METHANOL
CAS No.:86462-76-2
Molecular Formula:C₁₁H₂₄O₃Si
Molecular Weight:232.395
Hs Code.:
Mol file:86462-76-2.mol

Synonyms:((2R,3R)-3-[2-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-ETHYL]-OXIRANYL)-METHANOL

Suppliers and Price of ((2R,3R)-3-[2-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-ETHYL]-OXIRANYL)-METHANOL

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
((2R,3R)-3-(2-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-ETHYL)-OXIRANYL)-METHANOL 95.00%
5MG
$ 495.31

Total 3 raw suppliers

Chemical Property of ((2R,3R)-3-[2-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-ETHYL]-OXIRANYL)-METHANOL

Chemical Property:

PSA：41.99000
LogP:2.15800

Purity/Quality:

99% ^*data from raw suppliers

((2R,3R)-3-(2-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-ETHYL)-OXIRANYL)-METHANOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of ((2R,3R)-3-[2-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-ETHYL]-OXIRANYL)-METHANOL

There total 7 articles about ((2R,3R)-3-[2-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-ETHYL]-OXIRANYL)-METHANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 86462-75-1
(Z)-5-<(1,1-dimethylethyl)dimethylsilyloxy>pent-2-en-1-ol

: 86462-76-2
(2R,3S)-5-t-butyldimethylsilyloxy-2,3-epoxypentan-1-ol

Guidance literature:: With titanium(IV) isopropylate; tert.-butylhydroperoxide; diethyl (2S,3S)-tartrate; In dichloromethane; 1,2-dichloro-ethane; at -30 ℃; for 96h;
DOI:10.1002/hlca.19830660304

Reference yield:

: 86462-75-1
(Z)-5-<(1,1-dimethylethyl)dimethylsilyloxy>pent-2-en-1-ol

: 111466-32-1
(2S,3R)-4-t-butyldimethylsilyloxy-2,3-epoxy-pentan-1-ol

: 86462-76-2
(2R,3S)-5-t-butyldimethylsilyloxy-2,3-epoxypentan-1-ol

Guidance literature:: With diethyl (2R,3R)-tartrate; Yield given; Sharpless epoxidation;
DOI:10.1016/S0040-4020(01)89856-2

Reference yield:

: 90134-46-6
5-[(tert-butyldimethylsilyl)oxy]pent-2-yn-1-ol

: 86462-76-2
(2R,3S)-5-t-butyldimethylsilyloxy-2,3-epoxypentan-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Lindlar catalyst / benzene / Ambient temperature

2: 74 percent / (D)-(-)-DIPT, Ti(OiPr)4, TBHP, 4A MS / CH₂Cl₂ / 64 h / -30 °C

With titanium(IV) isopropylate; tert.-butylhydroperoxide; (-)-diisopropyl tartrate; hydrogen; Lindlar's catalyst; In dichloromethane; benzene;
DOI:10.1016/0040-4039(91)85089-N