111466-32-1

Upstream product

• 86462-75-1 (Z)-5-<(1,1-dimethylethyl)dimethylsilyloxy>pent-2-en-1-ol 

Downstream Products

• 111392-98-4 (S)-1-Benzyloxy-5-(tert-butyl-dimethyl-silanyloxy)-pentan-3-ol 
• 111466-34-3 3β-hydroxy-5β-<(2-phenyl)ethyl>-δ-lactone 
• 111393-01-2 Acetic acid (S)-5-benzyloxy-3-methoxymethoxy-1-phenethyl-pentyl ester 
• 111393-02-3 (R)-5-Acetoxy-3-methoxymethoxy-7-phenyl-heptanoic acid 
• 111392-99-5 ((S)-5-Benzyloxy-3-methoxymethoxy-pentyloxy)-tert-butyl-dimethyl-silane 
• 111393-00-1 (S)-5-Benzyloxy-3-methoxymethoxy-pentanal 
• 86117-01-3 (4R,6R)-(+)-4-hydroxy-6-(2-phenylethyl)-tetrahydro-2H-pyran-2-one 
• 144076-08-4 (3S,4R)-5-Benzyloxy-4-methyl-3-(toluene-4-sulfonylamino)-pentanoic acid 
• 144076-09-5 (S)-4-((R)-2-Benzyloxy-1-methyl-ethyl)-1-(toluene-4-sulfonyl)-azetidin-2-one 
• 144076-06-2 2-[(2S,3S)-3-Benzyloxymethyl-1-(toluene-4-sulfonyl)-aziridin-2-yl]-ethanol 
• 144076-07-3 N-[(1S,2R)-3-Benzyloxy-1-(2-hydroxy-ethyl)-2-methyl-propyl]-4-methyl-benzenesulfonamide 
• 144076-05-1 2-((2S,3S)-3-Benzyloxymethyl-aziridin-2-yl)-ethanol 
• 713141-46-9 7-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxy)-4-methyl-hept-2-enal 
• 147618-57-3 Toluene-4-sulfonic acid (2S,3R)-3-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-oxiranylmethyl ester 

Relevant academic research and scientific papers

Total synthesis of (-)-dactylynes

The first total synthesis of (-)-dactylyne (1) and (-)-isodactylyne (2), which have been isolated from sea hare, is described in detail. Critical steps in the synthesis include a stereoselective construction as well as an intramolecular ring closure of 32, and the effective double elongation reactions (59 → 63 and 64, 67 → 68, and 70 → 71).

Enantioselective Routes toward 1β-Methylcarbapenems from Chiral Aziridines

This paper describes two enantioselective aziridine-based routes toward 1β-methylthienamycin, 2, and related carbapenems, the key steps being completely regioselective ring-opening reactions of the chiral aziridines 7 and 10 with AlMe3. - Key Words: 1β-me