5,7-Difluoro-4-hydroxyquinoline

Base Information

Chemical Name:5,7-Difluoro-4-hydroxyquinoline
CAS No.:874804-43-0
Molecular Formula:C₉H₅F₂NO
Molecular Weight:181.142
Hs Code.:2933499090
European Community (EC) Number:804-526-9
DSSTox Substance ID:DTXSID30656135
Wikidata:Q82570646
Mol file:874804-43-0.mol

Synonyms:874804-43-0;5,7-Difluoro-4-hydroxyquinoline;5,7-Difluoroquinolin-4-ol;5,7-difluoro-1H-quinolin-4-one;5,7-Difluoro-4-quinolinol;SCHEMBL22972418;DTXSID30656135;5,7-Difluoroquinolin-4(1H)-one;ZJB80443;MFCD06409136;SB67429;CS-0253240;FT-0753009;5,7-Difluoro-4-hydroxyquinoline, AldrichCPR;EN300-629939;Z2757417264

Suppliers and Price of 5,7-Difluoro-4-hydroxyquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5,7-Difluoro-4-hydroxyquinoline
100mg
$ 60.00

TRC
5,7-Difluoro-4-hydroxyquinoline
50mg
$ 45.00

SynQuest Laboratories
5,7-Difluoro-4-hydroxyquinoline
1 g
$ 168.00

Sigma-Aldrich
5,7-Difluoro-4-hydroxyquinoline Aldrich
1g
$ 140.00

Apolloscientific
5,7-Difluoro-4-hydroxyquinoline
1g
$ 153.00

American Custom Chemicals Corporation
5,7-DIFLUORO-4-HYDROXYQUINOLINE 95.00%
1G
$ 295.05

AK Scientific
5,7-Difluoro-4-hydroxyquinoline
1g
$ 232.00

Total 3 raw suppliers

Chemical Property of 5,7-Difluoro-4-hydroxyquinoline

Chemical Property:

Vapor Pressure:0.000305mmHg at 25°C
Boiling Point:311.5°C at 760 mmHg
Flash Point:142.2°C
PSA：33.12000
Density:1.465g/cm³
LogP:2.21860
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:181.03392011
Heavy Atom Count:13
Complexity:254

Purity/Quality:

97% ^*data from raw suppliers

5,7-Difluoro-4-hydroxyquinoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22-41
Safety Statements: 26-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CNC2=C(C1=O)C(=CC(=C2)F)F

Technology Process of 5,7-Difluoro-4-hydroxyquinoline

There total 2 articles about 5,7-Difluoro-4-hydroxyquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 1071541-70-2
5-[(3,5-difluoro-phenylamino)-methylene]-2,2-dimethyl-[1,3]dioxane-4,6-dione

: 874804-43-0
5,7-difluoroquinolin-4-ol

Guidance literature:: In diphenylether; at 230 ℃; for 1h;

Reference yield:

: 372-39-4
3,5-difluoroaniline

: 874804-43-0
5,7-difluoroquinolin-4-ol

Guidance literature:: Multi-step reaction with 2 steps

1.1: 1 h / 105 °C / Inert atmosphere

1.2: 1 h / 105 °C / Inert atmosphere

2.1: diphenylether / 1 h / 230 °C

In diphenylether;