2,5-anhydro-4,6-di-O-benzoyl-3-deoxy-D-arabino-hexonic acid

Base Information

Chemical Name:2,5-anhydro-4,6-di-O-benzoyl-3-deoxy-D-arabino-hexonic acid
CAS No.:82462-50-8
Molecular Formula:C20H18O7
Molecular Weight:370.35
Hs Code.:
Mol file:82462-50-8.mol

Synonyms:2,5-anhydro-4,6-di-O-benzoyl-3-deoxy-D-arabino-hexonic acid;2,5-Anhydro-3-deoxy-D-arabino-hexonic acid dibenzoate

Suppliers and Price of 2,5-anhydro-4,6-di-O-benzoyl-3-deoxy-D-arabino-hexonic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 2,5-anhydro-4,6-di-O-benzoyl-3-deoxy-D-arabino-hexonic acid

Chemical Property:

Boiling Point:553.5±50.0 °C(Predicted)
PKA:3.08±0.60(Predicted)
PSA：99.13000
Density:1.36±0.1 g/cm3 (20 ºC 760 Torr)
LogP:2.31110

Purity/Quality:: 99.0% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2,5-anhydro-4,6-di-O-benzoyl-3-deoxy-D-arabino-hexonic acid

There total 7 articles about 2,5-anhydro-4,6-di-O-benzoyl-3-deoxy-D-arabino-hexonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 127676-66-8
C₂₀H₁₇NO₅

: 82462-50-8
2,5-anhydro-4,6-di-O-benzoyl-3-deoxy-D-arabino-hexonic acid

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; for 7h; Heating;
DOI:10.1246/cl.1992.1673

Reference yield:

: 82462-47-3
benzyl (4S,trans)-4-benzoyloxy-5-benzoyloxymethyl-4,5-dihydrofuran-2-carboxylate

: 82462-49-5
2,5-anhydro-4,6-di-O-benzoyl-3-deoxy-D-ribo-hexonic acid

: 82462-50-8
2,5-anhydro-4,6-di-O-benzoyl-3-deoxy-D-arabino-hexonic acid

Guidance literature:: With hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1016/S0040-4039(00)87008-2

Reference yield:

: 23316-68-9
(2R,3R,4R,5R)-3,4-bis(benzoyloxy)-5-((benzoyloxy)methyl)tetrahydrofuran-2-carboxylic acid

: 82462-50-8
2,5-anhydro-4,6-di-O-benzoyl-3-deoxy-D-arabino-hexonic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 73 percent / 1.) 2-chloro-N-methylpyridinium iodide, triethylamine / acetonitrile / Ambient temperature; 1.) 1.5 h, 2.) overnight

2: 34 percent / H₂ / 10percent Pd-C / ethanol / 48 h / 760 Torr

3: tetra-n-butylammonium fluoride / tetrahydrofuran / 22 h / Ambient temperature

With tetrabutyl ammonium fluoride; 2-chloro-1-methyl-pyridinium iodide; hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; ethanol; acetonitrile;
DOI:10.1039/P19850000621