1-(tert-butyl-dimethyl-silanyl)-5-fluoro-1H-indole

Base Information

Chemical Name:1-(tert-butyl-dimethyl-silanyl)-5-fluoro-1H-indole
CAS No.:1093066-71-7
Molecular Formula:C14H20FNSi
Molecular Weight:249
Hs Code.:
Mol file:1093066-71-7.mol

Synonyms:1-(tert-butyl-dimethyl-silanyl)-5-fluoro-1H-indole;1-(tert-butyl-dimethyl-silanyl)-5-fluoro-1H-indole-2;1-(tert-butyldimethylsilyl)-5-fluoro-1H-indole

Suppliers and Price of 1-(tert-butyl-dimethyl-silanyl)-5-fluoro-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ACHEMBLOCK
1-(tert-Butyldimethylsilyl)-5-fluoro-1H-indole 95%
1G
$ 270.00

ACHEMBLOCK
1-(tert-Butyldimethylsilyl)-5-fluoro-1H-indole 95%
250MG
$ 110.00

Total 3 raw suppliers

Chemical Property of 1-(tert-butyl-dimethyl-silanyl)-5-fluoro-1H-indole

Chemical Property:

PSA：4.93000
LogP:4.63370

Purity/Quality:

99% ^*data from raw suppliers

1-(tert-Butyldimethylsilyl)-5-fluoro-1H-indole 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-(tert-butyl-dimethyl-silanyl)-5-fluoro-1H-indole

There total 1 articles about 1-(tert-butyl-dimethyl-silanyl)-5-fluoro-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 399-52-0
5-fluoro-1H-indole

: 18162-48-6
tert-butyldimethylsilyl chloride

: 1093066-71-7
1-(tert-butyldimethylsilanyl)-5-fluoro-1H-indole

Guidance literature:: 5-fluoro-1H-indole; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; for 0.75h; Inert atmosphere;

tert-butyldimethylsilyl chloride; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; for 12h; Inert atmosphere;
DOI:10.1002/anie.201800494

Reference yield: 71.0%

: 1093066-71-7
1-(tert-butyldimethylsilanyl)-5-fluoro-1H-indole

: 1093066-72-8
[1-(tert-butyldimethylsilanyl)-5-fluoro-1H-indol-4-yl]boronic acid

Guidance literature:: 1-(tert-butyldimethylsilanyl)-5-fluoro-1H-indole; With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In tetrahydrofuran; cyclohexane; at -78 ℃; for 2h;

With Triisopropyl borate; In tetrahydrofuran; cyclohexane; at -78 - -20 ℃; for 0.666667h;

With hydrogenchloride; In tetrahydrofuran; cyclohexane; water;

Reference yield: 71.0%

: 5419-55-6
Triisopropyl borate

: 1093066-71-7
1-(tert-butyldimethylsilanyl)-5-fluoro-1H-indole

: 1093066-72-8
[1-(tert-butyldimethylsilanyl)-5-fluoro-1H-indol-4-yl]boronic acid

Guidance literature:: 1-(tert-butyldimethylsilanyl)-5-fluoro-1H-indole; With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In tetrahydrofuran; cyclohexane; at -78 ℃; for 2h;

Triisopropyl borate; In tetrahydrofuran; cyclohexane; at -78 - -10 ℃; for 0.25h;

With hydrogenchloride; In tetrahydrofuran; cyclohexane; water;