N-(2-aminoethyl)-4-methoxybenzenesulfonamide

Base Information

Chemical Name:N-(2-aminoethyl)-4-methoxybenzenesulfonamide
CAS No.:90566-22-6
Molecular Formula:C9H14N2O3S
Molecular Weight:230.288
Hs Code.:
DSSTox Substance ID:DTXSID80366914
Wikidata:Q82152390

Synonyms:N-(2-aminoethyl)-4-methoxybenzenesulfonamide;90566-22-6;CHEMBRDG-BB 7436664;SCHEMBL15145873;DTXSID80366914;STK257461;AKOS009151644;CS-0302892;EN300-29604;N-(2-aminoethyl)-4-methoxybenzene-1-sulfonamide;SR-01000262448;SR-01000262448-1

Suppliers and Price of N-(2-aminoethyl)-4-methoxybenzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of N-(2-aminoethyl)-4-methoxybenzenesulfonamide

Chemical Property:

Vapor Pressure:2.95E-06mmHg at 25°C
Boiling Point:389°C at 760 mmHg
Flash Point:189°C
Density:1.25g/cm³
XLogP3:-0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:230.07251349
Heavy Atom Count:15
Complexity:266

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)S(=O)(=O)NCCN

Technology Process of N-(2-aminoethyl)-4-methoxybenzenesulfonamide

There total 6 articles about N-(2-aminoethyl)-4-methoxybenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 107-15-3,85404-18-8
ethylenediamine

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 90566-22-6
N-(2-aminoethyl)-4-methoxybenzenesulfonamide

Guidance literature:: With triethylamine; In dichloromethane; at 0 ℃;
DOI:10.1021/acs.jmedchem.1c00230

Reference yield:

: 2576-47-8
2-bromoethylamine hydrobromide

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 90566-22-6
N-(2-aminoethyl)-4-methoxybenzenesulfonamide

Guidance literature:: With sodium hydrogencarbonate; In tetrahydrofuran; water; at 55 - 60 ℃; for 6h;

Reference yield:

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 90566-22-6
N-(2-aminoethyl)-4-methoxybenzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0 °C

2: palladium on activated charcoal; hydrogen / methanol / 2 h / 20 °C

With palladium on activated charcoal; hydrogen; N-ethyl-N,N-diisopropylamine; In methanol; dichloromethane;
DOI:10.1016/j.bioorg.2021.105424