5-[(2-Propynyloxy)methyl]-3-[4-(trifluoromethyl)phenyl]-2-oxazolidinone

Base Information

Chemical Name:5-[(2-Propynyloxy)methyl]-3-[4-(trifluoromethyl)phenyl]-2-oxazolidinone
CAS No.:23598-48-3
Molecular Formula:C₁₄H₁₂F₃NO₃
Molecular Weight:299.249
Hs Code.:2934999090
Mol file:23598-48-3.mol

Synonyms:2-Oxazolidinone,5-[(2-propynyloxy)methyl]-3-(a,a,a-trifluoro-p-tolyl)- (8CI); 2-Oxazolidinone,5-[(2-propynyloxy)methyl]-3-[4-(trifluoromethyl)phenyl]- (9CI); MD 67132;Propargyloxymethyl-5-p-trifluoromethylphenyl-3-oxazolidinone-2

Suppliers and Price of 5-[(2-Propynyloxy)methyl]-3-[4-(trifluoromethyl)phenyl]-2-oxazolidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 5-[(2-Propynyloxy)methyl]-3-[4-(trifluoromethyl)phenyl]-2-oxazolidinone

Chemical Property:

Vapor Pressure:9.28E-06mmHg at 25°C
Boiling Point:372.9°Cat760mmHg
Flash Point:179.3°C
PSA：38.77000
Density:1.325g/cm³
LogP:2.74540

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-[(2-Propynyloxy)methyl]-3-[4-(trifluoromethyl)phenyl]-2-oxazolidinone

There total 6 articles about 5-[(2-Propynyloxy)methyl]-3-[4-(trifluoromethyl)phenyl]-2-oxazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 33212-04-3
(4-trifluoromethyl-phenyl)-carbamic acid 1-chloromethyl-2-prop-2-ynyloxy-ethyl ester

: 23598-48-3
5-prop-2-ynyloxymethyl-3-(4-trifluoromethyl-phenyl)-oxazolidin-2-one

Guidance literature:: With potassium hydroxide; In ethanol; at 40 ℃; for 1h;

Reference yield:

: 75-44-5
phosgene

: 23452-80-4
1-prop-2-ynyloxy-3-(4-trifluoromethyl-anilino)-propan-2-ol

: 23598-48-3
5-prop-2-ynyloxymethyl-3-(4-trifluoromethyl-phenyl)-oxazolidin-2-one

Guidance literature:: With potassium carbonate; In toluene; at 40 ℃; for 3h;

Reference yield:

: 455-14-1
4-trifluoromethylphenylamine

: 23598-48-3
5-prop-2-ynyloxymethyl-3-(4-trifluoromethyl-phenyl)-oxazolidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: (i) toluene, PhNEt₂, (ii) /BRN= 1564853/

2: aq. KOH / ethanol / 1 h / 40 °C

With potassium hydroxide; In ethanol;