1-(Prop-2-yn-1-yl)piperidin-2-one

Base Information

Chemical Name:1-(Prop-2-yn-1-yl)piperidin-2-one
CAS No.:18327-29-2
Molecular Formula:C₈H₁₁NO
Molecular Weight:137.181
Hs Code.:
DSSTox Substance ID:DTXSID90534965
Nikkaji Number:J2.211.291K
Wikidata:Q82409030
Mol file:18327-29-2.mol

Synonyms:1-(prop-2-yn-1-yl)piperidin-2-one;18327-29-2;1-prop-2-ynylpiperidin-2-one;1-(2-propynyl)-2-piperidone;SCHEMBL2705010;DTXSID90534965;CKLYEKVPUJOEPJ-UHFFFAOYSA-N;AKOS010600699;EN300-100077;G31174;Z804946048

Suppliers and Price of 1-(Prop-2-yn-1-yl)piperidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-(Prop-2-yn-1-yl)piperidin-2-one

Chemical Property:

XLogP3:0.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:137.084063974
Heavy Atom Count:10
Complexity:177

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C#CCN1CCCCC1=O

Technology Process of 1-(Prop-2-yn-1-yl)piperidin-2-one

There total 1 articles about 1-(Prop-2-yn-1-yl)piperidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 675-20-7
piperidin-2-one

: 106-96-7
propargyl bromide

: 18327-29-2
N-propargyl δ-valerolactam

: 214219-69-9
N-(1,2-propadienyl)valerolactam

Guidance literature:: With potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate; In tetrahydrofuran; for 4h; Heating;
DOI:10.1016/j.tetlet.2005.07.013

Reference yield: 60.0%

: 18327-29-2
N-propargyl δ-valerolactam

: N-(((chloromethyl)dimethylsilyl)methyl)-4-methylbenzenesulfonamide

: 1-((3,3-dimethyl-1-tosyl-1,2,3,6-tetrahydro-1,3-azasilin-5-yl)methyl)piperidin-2-one

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; zinc(II) iodide; In 5,5-dimethyl-1,3-cyclohexadiene; at 120 ℃; for 0.166667h; Glovebox; Sealed tube;
DOI:10.1021/jacs.1c04667