3-Thiophenecarboxylicacid,2-amino-5-cyclopropyl-,methylester(9CI)

Base Information

Chemical Name:3-Thiophenecarboxylicacid,2-amino-5-cyclopropyl-,methylester(9CI)
CAS No.:439692-97-4
Molecular Formula:C9H11NO2S
Molecular Weight:0
Hs Code.:
Mol file:439692-97-4.mol

Synonyms:3-Thiophenecarboxylicacid,2-amino-5-cyclopropyl-,methylester(9CI)

Suppliers and Price of 3-Thiophenecarboxylicacid,2-amino-5-cyclopropyl-,methylester(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Arctom
Methyl2-amino-5-cyclopropylthiophene-3-carboxylate
1g
$ 1286.00

AK Scientific
Methyl2-amino-5-cyclopropylthiophene-3-carboxylate
2.5g
$ 2705.00

AK Scientific
Methyl2-amino-5-cyclopropylthiophene-3-carboxylate
250mg
$ 757.00

Total 3 raw suppliers

Chemical Property of 3-Thiophenecarboxylicacid,2-amino-5-cyclopropyl-,methylester(9CI)

Chemical Property:

PSA：80.56000
LogP:2.57550

Purity/Quality:

97% ^*data from raw suppliers

Methyl2-amino-5-cyclopropylthiophene-3-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-Thiophenecarboxylicacid,2-amino-5-cyclopropyl-,methylester(9CI)

There total 2 articles about 3-Thiophenecarboxylicacid,2-amino-5-cyclopropyl-,methylester(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 56105-19-2
2-cyclopropylacetaldehyde

: 105-34-0
methyl 2-cyanoacetate

: 439692-97-4
methyl 2-amino-5-cyclopropylthiophene-3-carboxylate

Guidance literature:: With sulfur; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 40.1667h; Inert atmosphere;
DOI:10.1248/cpb.59.991

Reference yield:

: 2566-44-1
1-cyclopropylethanol

: 439692-97-4
methyl 2-amino-5-cyclopropylthiophene-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: pyridinium chlorochromate / dichloromethane / 1.5 h / 20 °C / Inert atmosphere

2: sulfur; triethylamine / N,N-dimethyl-formamide / 40.17 h / 20 °C / Inert atmosphere

With sulfur; triethylamine; pyridinium chlorochromate; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1248/cpb.59.991

Reference yield:

: 32315-10-9
bis(trichloromethyl) carbonate

: 439692-97-4
methyl 2-amino-5-cyclopropylthiophene-3-carboxylate

: 1583-88-6
4-fluoro-2-phenethylamine

: 1084627-95-1
C₁₇H₁₅FN₂O₂S

Guidance literature:: bis(trichloromethyl) carbonate; methyl 2-amino-5-cyclopropylthiophene-3-carboxylate; With triethylamine; In dichloromethane; at 1 - 30 ℃; for 2h;

4-fluoro-2-phenethylamine; In dichloromethane; at 1 - 30 ℃; for 1h;

With sodium methylate; In methanol; at 60 ℃; for 1h;