1-(5-Fluoro-2,4-dinitrophenyl)-4-methylpiperazine

Base Information

• Chemical Name: 1-(5-Fluoro-2,4-dinitrophenyl)-4-methylpiperazine
• CAS No.: 928830-73-3
• Molecular Formula: C11H13FN4O4
• Molecular Weight: 284.24
• Hs Code.: 2933599090
• DSSTox Substance ID: DTXSID60585323
• Wikidata: Q82477245
• Mol file: 928830-73-3.mol

Synonyms:1-(5-Fluoro-2,4-dinitrophenyl)-4-methylpiperazine;928830-73-3;Piperazine, 1-(5-fluoro-2,4-dinitrophenyl)-4-methyl-;SCHEMBL15800716;DTXSID60585323;MFCD10000959;AKOS028109885;T73076;1-(2,4-dinitro-5-fluorophenyl)-4-methylpiperazine

Chemical Property of 1-(5-Fluoro-2,4-dinitrophenyl)-4-methylpiperazine

Chemical Property:

• Melting Point: 115 °C
• PSA: 98.12000
• LogP: 2.44320
• Storage Temp.: Refrigerator, under inert atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly)
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 1
• Exact Mass: 284.09208307
• Heavy Atom Count: 20
• Complexity: 378

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-(5-Fluoro-2,4-dinitrophenyl)-4-methylpiperazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN1CCN(CC1)C2=CC(=C(C=C2[N+](=O)[O-])[N+](=O)[O-])F

Technology Process of 1-(5-Fluoro-2,4-dinitrophenyl)-4-methylpiperazine

There total 1 articles about 1-(5-Fluoro-2,4-dinitrophenyl)-4-methylpiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-methyl-piperazine (109-01-3) + 1,5-difluoro-2,4-dinitrobenzene (327-92-4) → 1-(5-fluoro-2, 4- dinitrophenyl)-4- methylpiperazine (928830-73-3)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃;

DOI:10.1016/j.ejmech.2014.01.039

Reference yield:

1-(5-fluoro-2, 4- dinitrophenyl)-4- methylpiperazine (928830-73-3) + n-Pentylamine (110-58-7) → C16H25N5O4 (1580534-55-9)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃;

DOI:10.1016/j.ejmech.2014.01.039

Reference yield:

1-(5-fluoro-2, 4- dinitrophenyl)-4- methylpiperazine (928830-73-3) + 3-methoxypropylamine (5332-73-0) → C15H23N5O5 (1465826-21-4)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃;

DOI:10.1016/j.ejmech.2014.01.039

upstream raw materials:

1-methyl-piperazine

1,5-difluoro-2,4-dinitrobenzene

Downstream raw materials:

C₁₅H₂₃N₅O₅

1-(4-methoxyphenyl)-3-(1-(3-methoxypropyl)-6-(4-methylpiperazin-1-yl)-2-(5-nitrofuran-2-yl)-1H-benzo[d]imidazol-5-yl)urea

1-(4-fluorophenyl)-3-(1-(3-methoxypropyl)-6-(4-methylpiperazin-1-yl)-2-(5-nitrofuran-2-yl)-1H-benzo[d]imidazol-5-yl)urea

1-(4-methoxyphenyl)-3-(1-(3-methoxypropyl)-6-(4-methylpiperazin-1-yl)-2-(5-nitrofuran-2-yl)-1H-benzo[d]imidazol-5-yl)thiourea