7-Hydroxynaphthalene-1-carbaldehyde

Base Information

Chemical Name:7-Hydroxynaphthalene-1-carbaldehyde
CAS No.:144876-32-4
Molecular Formula:C11H8O2
Molecular Weight:172.18002
Hs Code.:
DSSTox Substance ID:DTXSID50572888
Wikidata:Q82461394
Mol file:144876-32-4.mol

Synonyms:144876-32-4;7-hydroxynaphthalene-1-carbaldehyde;7-Hydroxynaphthalene-1-carboxaldehyde;7-hydroxy-1-naphthaldehyde;SCHEMBL9669003;DTXSID50572888;MFCD17012512;AS-82523;SY156456;E78793;EN300-139899;Z1255397916

Suppliers and Price of 7-Hydroxynaphthalene-1-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-hydroxynaphthalene-1-carbaldehyde
5mg
$ 65.00

Alichem
5-Naphthol-2-carboxaldehyde
500mg
$ 940.80

Total 5 raw suppliers

Chemical Property of 7-Hydroxynaphthalene-1-carbaldehyde

Chemical Property:

Boiling Point:373.4±15.0 °C(Predicted)
PKA:8.47±0.40(Predicted)
PSA：37.30000
Density:1.288±0.06 g/cm3(Predicted)
LogP:2.35790
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:172.052429494
Heavy Atom Count:13
Complexity:191

Purity/Quality:

95% ^*data from raw suppliers

7-hydroxynaphthalene-1-carbaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C(C=C2)O)C(=C1)C=O

Technology Process of 7-Hydroxynaphthalene-1-carbaldehyde

There total 10 articles about 7-Hydroxynaphthalene-1-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₂H₇F₃O₄S

: 144876-32-4
7-hydroxy-1-naphthaldehyde

Guidance literature:: With potassium hydroxide; In ethanol; at 65 ℃; for 3h;
DOI:10.1021/jacs.1c05709 DOI:10.1021/jacs.1c10524

Reference yield:

: 135-19-3
β-naphthol

: 144876-32-4
7-hydroxy-1-naphthaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1.1: pyridine / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere

2.1: titanium tetrachloride / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere

2.2: 0 °C

3.1: potassium hydroxide / ethanol / 3 h / 65 °C

With pyridine; titanium tetrachloride; potassium hydroxide; In ethanol; dichloromethane;
DOI:10.1021/jacs.1c05709 DOI:10.1021/jacs.1c10524

Reference yield:

: 3857-83-8
2-naphthyl triflate

: 144876-32-4
7-hydroxy-1-naphthaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: titanium tetrachloride / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere

1.2: 0 °C

2.1: potassium hydroxide / ethanol / 3 h / 65 °C

With titanium tetrachloride; potassium hydroxide; In ethanol; dichloromethane;
DOI:10.1021/jacs.1c05709 DOI:10.1021/jacs.1c10524