1-(2-Aminopyridin-4-yl)ethanone

Base Information

Chemical Name:1-(2-Aminopyridin-4-yl)ethanone
CAS No.:42182-25-2
Molecular Formula:C7H8N2O
Molecular Weight:136
Hs Code.:2933399090
DSSTox Substance ID:DTXSID00521846
Wikidata:Q82386609
Mol file:42182-25-2.mol

Synonyms:1-(2-Aminopyridin-4-yl)ethanone;42182-25-2;1-(2-AMINOPYRIDIN-4-YL)ETHAN-1-ONE;1-(2-amino-4-pyridyl)-1-ethanone;1-(2-AMINO-4-PYRIDINYL)ETHANONE;1-(2-AMINO-PYRIDIN-4-YL)-ETHANONE;SCHEMBL1159738;DTXSID00521846;OZNURVDNAKVKGM-UHFFFAOYSA-N;MFCD13188958;AKOS006360296;AB67454;CS-W021199;AS-42004

Suppliers and Price of 1-(2-Aminopyridin-4-yl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(2-Aminopyridin-4-yl)ethanone
100mg
$ 155.00

Crysdot
1-(2-Aminopyridin-4-yl)ethanone 97%
1g
$ 574.00

Crysdot
1-(2-Aminopyridin-4-yl)ethanone 97%
5g
$ 1025.00

Chemenu
1-(2-aminopyridin-4-yl)ethan-1-one 97%
5g
$ 968.00

Chemcia Scientific
1-(2-Amino-pyridin-4-yl)-ethanone ＞97%
1 G
$ 1250.00

American Custom Chemicals Corporation
1-(2-AMINOPYRIDIN-4-YL)ETHANONE 95.00%
5MG
$ 496.73

Ambeed
1-(2-Aminopyridin-4-yl)ethanone 97%
1g
$ 637.00

Ambeed
1-(2-Aminopyridin-4-yl)ethanone 97%
50mg
$ 142.00

Ambeed
1-(2-Aminopyridin-4-yl)ethanone 97%
25mg
$ 97.00

Ambeed
1-(2-Aminopyridin-4-yl)ethanone 97%
250mg
$ 318.00

Total 17 raw suppliers

Chemical Property of 1-(2-Aminopyridin-4-yl)ethanone

Chemical Property:

Melting Point:133-133.5 °C
Boiling Point:318.1±22.0 °C(Predicted)
PKA:4.60±0.11(Predicted)
PSA：56.71000
Density:1.168±0.06 g/cm3(Predicted)
LogP:0.79650
Storage Temp.:2-8°C(protect from light)
XLogP3:0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:136.063662883
Heavy Atom Count:10
Complexity:136

Purity/Quality:

99%, ^*data from raw suppliers

1-(2-Aminopyridin-4-yl)ethanone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=CC(=NC=C1)N

Technology Process of 1-(2-Aminopyridin-4-yl)ethanone

There total 9 articles about 1-(2-Aminopyridin-4-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 42182-25-2
1-(2-amino-4-pyridyl)-1-ethanone

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; In N,N-dimethyl-formamide; at 110 ℃; for 1.5h; Inert atmosphere; Sealed tube;

Reference yield: 20.0%

: 6937-03-7
methyl 2-aminoisonicotinate

: 917-54-4
methyllithium

: 42182-25-2
1-(2-amino-4-pyridyl)-1-ethanone

Guidance literature:: In tetrahydrofuran; diethyl ether; at -78 - 0 ℃; for 3.5h;
DOI:10.1021/acs.jmedchem.5b01029

Reference yield:

: 75-16-1
methylmagnesium bromide

: 42182-27-4
4-cyanopyridin-2-amine

: 42182-25-2
1-(2-amino-4-pyridyl)-1-ethanone

Guidance literature:: methylmagnesium bromide; 4-cyanopyridin-2-amine; In diethyl ether; at 0 ℃; Reflux;

With water; In diethyl ether; Cooling;