2-Methyl-4-((tetrahydro-2H-pyran-2-yl)oxy)-6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde

Base Information

Chemical Name:2-Methyl-4-((tetrahydro-2H-pyran-2-yl)oxy)-6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde
CAS No.:1265359-19-0
Molecular Formula:C19H27BO5
Molecular Weight:346.231
Hs Code.:
Mol file:1265359-19-0.mol

Synonyms:2-Methyl-4-((tetrahydro-2H-pyran-2-yl)oxy)-6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde

Suppliers and Price of 2-Methyl-4-((tetrahydro-2H-pyran-2-yl)oxy)-6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Methyl-4-((tetrahydro-2H-pyran-2-yl)oxy)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde 97%
250mg
$ 260.00

Crysdot
2-Methyl-4-((tetrahydro-2H-pyran-2-yl)oxy)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde 97%
1g
$ 650.00

Chemenu
2-Methyl-4-((tetrahydro-2H-pyran-2-yl)oxy)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde 97%
1g
$ 645.00

Total 3 raw suppliers

Chemical Property of 2-Methyl-4-((tetrahydro-2H-pyran-2-yl)oxy)-6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde

Chemical Property:

Boiling Point:503.3±50.0 °C(Predicted)
PSA：53.99000
Density:1.12±0.1 g/cm3(Predicted)
LogP:3.01210

Purity/Quality:

99% ^*data from raw suppliers

2-Methyl-4-((tetrahydro-2H-pyran-2-yl)oxy)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-Methyl-4-((tetrahydro-2H-pyran-2-yl)oxy)-6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde

There total 5 articles about 2-Methyl-4-((tetrahydro-2H-pyran-2-yl)oxy)-6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 1265359-17-8
2-formyl-3-methyl-5-(tetrahydro-2H-pyran-2-yloxy)phenyl trifluoromethanesulfonate

: 73183-34-3
bis(pinacol)diborane

: 1265359-19-0
2-methyl-4-(tetrahydro-2H-pyran-2-yloxy)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde

Guidance literature:: With potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane; at 80 ℃; for 1h; Product distribution / selectivity; Inert atmosphere;

Reference yield:

: 487-69-4
2,4-dihydroxy-6-methylbenzaldehyde

: 1265359-19-0
2-methyl-4-(tetrahydro-2H-pyran-2-yloxy)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: pyridinium p-toluenesulfonate / dichloromethane / 18 h / 20 °C

2: pyridine / dichloromethane / 3 h / -10 - 0 °C

3: potassium acetate; palladium bis[bis(diphenylphosphino)ferrocene] dichloride / 1,4-dioxane / 1 h / 80 °C / Inert atmosphere

With pyridine; palladium bis[bis(diphenylphosphino)ferrocene] dichloride; potassium acetate; pyridinium p-toluenesulfonate; In 1,4-dioxane; dichloromethane;

Reference yield:

: 219298-65-4
2-hydroxy-6-methyl-4-(tetrahydropyran-2-yloxy)benzaldehyde

: 1265359-19-0
2-methyl-4-(tetrahydro-2H-pyran-2-yloxy)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / dichloromethane / 3 h / -10 - 0 °C

2: potassium acetate; palladium bis[bis(diphenylphosphino)ferrocene] dichloride / 1,4-dioxane / 1 h / 80 °C / Inert atmosphere

With pyridine; palladium bis[bis(diphenylphosphino)ferrocene] dichloride; potassium acetate; In 1,4-dioxane; dichloromethane;