1-PYRROLIDINECARBOXYLIC ACID, 3-AMINO-4-(HYDROXYMETHYL)-, PHENYLMETHYL ESTER, (3R,4R)-

Base Information

Chemical Name:1-PYRROLIDINECARBOXYLIC ACID, 3-AMINO-4-(HYDROXYMETHYL)-, PHENYLMETHYL ESTER, (3R,4R)-
CAS No.:255823-06-4
Molecular Formula:C₁₃H₁₈N₂O₃
Molecular Weight:250.298
Hs Code.:
Mol file:255823-06-4.mol

Synonyms:1-PYRROLIDINECARBOXYLIC ACID, 3-AMINO-4-(HYDROXYMETHYL)-, PHENYLMETHYL ESTER, (3R,4R)-;(3R,4R)-3-Amino-4-(hydroxymethyl)-1-pyrrolidinecarboxylic acid phenylmethyl ester;(3S,4S)-benzyl 3-aMino-4-(hydroxyMethyl)pyrrolidine-1-carboxylate (S)-2-hydroxy-2-phenylacetate

Suppliers and Price of 1-PYRROLIDINECARBOXYLIC ACID, 3-AMINO-4-(HYDROXYMETHYL)-, PHENYLMETHYL ESTER, (3R,4R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
(3S,4S)-benzyl3-amino-4-(hydroxymethyl)pyrrolidine-1-carboxylate(S)-2-hydroxy-2-phenylacetate
100mg
$ 252.00

ChemScene
(3S,4S)-benzyl3-amino-4-(hydroxymethyl)pyrrolidine-1-carboxylate(S)-2-hydroxy-2-phenylacetate
1g
$ 1482.00

American Custom Chemicals Corporation
(3R,4R)-3-AMINO-4-(HYDROXYMETHYL)-1-PYRROLIDINECARBOXYLIC ACID PHENYLMETHYL ESTER 95.00%
5MG
$ 496.09

Total 7 raw suppliers

Chemical Property of 1-PYRROLIDINECARBOXYLIC ACID, 3-AMINO-4-(HYDROXYMETHYL)-, PHENYLMETHYL ESTER, (3R,4R)-

Chemical Property:

Boiling Point:414.3±40.0 °C(Predicted)
PKA:14.93±0.10(Predicted)
PSA：75.79000
Density:1.225
LogP:1.21280

Purity/Quality:

97% ^*data from raw suppliers

(3S,4S)-benzyl3-amino-4-(hydroxymethyl)pyrrolidine-1-carboxylate(S)-2-hydroxy-2-phenylacetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-PYRROLIDINECARBOXYLIC ACID, 3-AMINO-4-(HYDROXYMETHYL)-, PHENYLMETHYL ESTER, (3R,4R)-

There total 27 articles about 1-PYRROLIDINECARBOXYLIC ACID, 3-AMINO-4-(HYDROXYMETHYL)-, PHENYLMETHYL ESTER, (3R,4R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: benzyl (4aR,7aR)-2,2-dimethylhexahydropyrrolo[3,4-d][1,3]oxazine-6(4H)-carboxylate (S)-mandelate

: 252770-09-5,255823-06-4
benzyl (3R,4R)-3-amino-4-(hydroxymethyl)pyrrolidine-1-carboxylate

Guidance literature:: benzyl (4aR,7aR)-2,2-dimethylhexahydropyrrolo[3,4-d][1,3]oxazine-6(4H)-carboxylate (S)-mandelate; With sulfuric acid; In ethanol; at 20 ℃; for 3h;

With sodium hydroxide; In ethanol;

Reference yield: 60.0%

: 370880-76-5
benzyl N-[2-(hydroxyimino)ethyl]-N-(prop-2-en-1-yl)carbamate

: 252770-09-5,255823-06-4
benzyl (cis)-3-amino-4-(hydroxymethyl)-1-pyrrolidinecarboxylate

Guidance literature:: benzyl N-[2-(hydroxyimino)ethyl]-N-(prop-2-en-1-yl)carbamate; In xylene; for 10h; Heating / reflux;

With acetic acid; zinc; In water; at 10 - 20 ℃; for 3.16667h;

With sodium carbonate; In water; pH=9 - 10;