p-Hydroxy Benzphetamine

Base Information

Chemical Name:p-Hydroxy Benzphetamine
CAS No.:87182-32-9
Molecular Formula:C17H21NO
Molecular Weight:255.35474
Hs Code.:
Mol file:87182-32-9.mol

Synonyms:p-Hydroxy Benzphetamine;1-(p-Hydroxyphenyl)-2-(N-Methyl-N-benzylaMino)propane;4-[2-[Methyl(phenylMethyl)aMino]propyl]phenol;p-HBMA

Suppliers and Price of p-Hydroxy Benzphetamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of p-Hydroxy Benzphetamine

Chemical Property:

Melting Point:113-116°C
PSA：23.47000
LogP:3.45520
Storage Temp.:-20°C Freezer

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses A metabolite of Benzphetamine.

Technology Process of p-Hydroxy Benzphetamine

There total 7 articles about p-Hydroxy Benzphetamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 864160-20-3
1-(4-tert-butyldimethylsiloxyphenyl)-2-N-benzyl-N-methylaminopropane

: 87182-32-9
1-(4-hydroxyphenyl)-2-N-benzyl-N-methylaminopropane

Guidance literature:: With sulfuric acid; In methanol; at 20 ℃; for 3.5h;
DOI:10.1248/cpb.53.684

Reference yield:

: 620600-27-3
1-(4-((tert-butyldimethylsilyl)oxy)phenyl)propan-2-one

: 87182-32-9
1-(4-hydroxyphenyl)-2-N-benzyl-N-methylaminopropane

Guidance literature:: Multi-step reaction with 2 steps

1: 51 percent / HCl; NaBH₃CN / methanol / 24 h / 20 °C

2: 83 percent / H₂SO₄ / methanol / 3.5 h / 20 °C

With hydrogenchloride; sulfuric acid; sodium cyanoborohydride; In methanol;
DOI:10.1248/cpb.53.684

Reference yield:

: 864160-19-0
2-(4-tert-butyldimethylsiloxyphenyl)propanol

: 87182-32-9
1-(4-hydroxyphenyl)-2-N-benzyl-N-methylaminopropane

Guidance literature:: Multi-step reaction with 3 steps

1: 83 percent / (COCl)2; DMSO; Et₃N / CH₂Cl₂ / 2 h / -78 - -20 °C

2: 51 percent / HCl; NaBH₃CN / methanol / 24 h / 20 °C

3: 83 percent / H₂SO₄ / methanol / 3.5 h / 20 °C

With hydrogenchloride; oxalyl dichloride; sulfuric acid; sodium cyanoborohydride; dimethyl sulfoxide; triethylamine; In methanol; dichloromethane; 1: Swern oxidation;
DOI:10.1248/cpb.53.684