FMOC-ARG(MTR)-N(OCH3)CH3

Base Information

• Chemical Name: FMOC-ARG(MTR)-N(OCH3)CH3
• CAS No.: 210532-73-3
• Molecular Formula: C₃₃H₄₁N₅O₇S
• Molecular Weight: 651.784
• Mol file: 210532-73-3.mol

Synonyms:N-ALPHA-FMOC-NG-(4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONYL)-L-ARGININE N-METHOXY-N-METHYL AMIDE;FMOC-ARG(MTR)-N(OCH3)CH3;FMOC-N-OMEGA-(4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONYL)-L-ARGININE N-METHOXY-N-METHYL AMIDE;N-[(1S)-4-[[Imino[[(4-methoxy-2,3,6-trimethylphenyl)sulfonyl]amino]methyl]amino]-1-[(methoxymethylamino)carbonyl]butyl]carbamic acid 9H-fluoren-9-ylmethyl ester

Chemical Property of FMOC-ARG(MTR)-N(OCH3)CH3

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of FMOC-ARG(MTR)-N(OCH3)CH3

There total 1 articles about FMOC-ARG(MTR)-N(OCH3)CH3 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

N,O-dimethylhydroxylamine*hydrochloride (6638-79-5) + Nα-(9-fluorenylmethoxycarbonyl)-Nγ-(4-methoxy-2,3,6-trimethylbenzenesulphonyl)-L-arginine (98930-01-9) → N-α-(9-fluorenylmethyloxycarbonyl)-N'-ω'-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine-N,O-dimethylhydroxyamide (210532-73-3)

Guidance literature:

With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1016/j.tet.2007.06.082

upstream raw materials:

N,O-dimethylhydroxylamine*hydrochloride

Nα-(9-fluorenylmethoxycarbonyl)-Nγ-(4-methoxy-2,3,6-trimethylbenzenesulphonyl)-L-arginine

Refernces

• 1、 Konno, Hiroyuki,Kubo, Kanako,Makabe, Hidefumi,Toshiro, Emi,Hinoda, Naoyuki,Nosaka, Kazuto,Akaji, Kenichi. "Total synthesis of miraziridine A and identification of its major reaction site for cathepsin B". . p. 9502 - 9513. Retrieved 2008/02/12.