Simvastatin Hydroxy Acid Methyl Ester

Base Information

Chemical Name:Simvastatin Hydroxy Acid Methyl Ester
CAS No.:145576-26-7
Molecular Formula:C₂₆H₄₂O₆
Molecular Weight:450.616
Hs Code.:
DSSTox Substance ID:DTXSID70453246
Nikkaji Number:J2.246.799I
Wikidata:Q82274353
Mol file:145576-26-7.mol

Synonyms:Simvastatin Hydroxy Acid Methyl Ester;145576-26-7;methyl (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-(2,2-dimethylbutanoyloxy)-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate;DTXSID70453246;J-008127;2,2-Dimethylbutyric acid (1S)-3beta,7alpha-dimethyl-8alpha-[(3R,5R)-3,5-dihydroxy-6-(methoxycarbonyl)hexyl]-1,2,3,7,8,8aalpha-hexahydronaphthalene-1beta-yl ester

Suppliers and Price of Simvastatin Hydroxy Acid Methyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
SimvastatinHydroxyAcidMethylEster
10mg
$ 245.00

Biosynth Carbosynth
Simvastatin hydroxy acid methyl ester
50 mg
$ 1201.50

Biosynth Carbosynth
Simvastatin hydroxy acid methyl ester
25 mg
$ 661.00

Biosynth Carbosynth
Simvastatin hydroxy acid methyl ester
10 mg
$ 363.50

Biosynth Carbosynth
Simvastatin hydroxy acid methyl ester
5 mg
$ 199.90

Biosynth Carbosynth
Simvastatin hydroxy acid methyl ester
100 mg
$ 2184.00

American Custom Chemicals Corporation
SIMVASTATIN METHYL ESTER 95.00%
0.5G
$ 1787.50

Total 10 raw suppliers

Chemical Property of Simvastatin Hydroxy Acid Methyl Ester

Chemical Property:

Boiling Point:575.4±50.0 °C(Predicted)
PKA:13.65±0.20(Predicted)
PSA：93.06000
Density:1.10±0.1 g/cm3(Predicted)
LogP:4.19410
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
XLogP3:4.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:12
Exact Mass:450.29813906
Heavy Atom Count:32
Complexity:709

Purity/Quality:

98%min ^*data from raw suppliers

SimvastatinHydroxyAcidMethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCC(C)(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC(CC(CC(=O)OC)O)O)C
Isomeric SMILES:CCC(C)(C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)OC)O)O)C
Uses An impurity in Simvastatin (S485000) tablets. An impurity in Simvastatin (S485000) tablets

Technology Process of Simvastatin Hydroxy Acid Methyl Ester

There total 4 articles about Simvastatin Hydroxy Acid Methyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%